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Books > Professional & Technical > Industrial chemistry & manufacturing technologies > Industrial chemistry > Pharmaceutical technology
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Comprehensive Analysis of Parasite Biology - From Metabolism to Drug Discovery (Hardcover)
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Comprehensive Analysis of Parasite Biology - From Metabolism to Drug Discovery (Hardcover)
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Written and edited by experts in the field, this book brings
together the current state of the art in phenotypic and rational,
target-based approaches to drug discovery against pathogenic
protozoa. The chapters focus particularly on virtual compounds and
high throughput screening, natural products, computer-assisted drug
design, structure-based drug design, mechanism of action
identification, and pathway modelling. Furthermore, state-of the
art "omics" technologies are described and currently studied
enzymatic drug targets are discussed. Mathematical, systems
biology-based approaches are introduced as new methodologies for
dissecting complex aspects of pathogen survival mechanisms and for
target identification. In addition, recently developed
anti-parasitic agents targeting particular pathways, which serve as
lead compounds for further drug development, are presented.
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