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Formulation and Evaluation of ER Tablet of Antipsychotic Drug (Paperback)
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Formulation and Evaluation of ER Tablet of Antipsychotic Drug (Paperback)
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The antipsychotic drugs are being used mainly for treatment of
schizophrenia. Schizophrenia is a mental disorder characterized by
a breakdown of typical emotional responses. Modified drug delivery
systems (MDDS) of antipsychotics offer advantages over conventional
formulations in provison of convenience, side effects and efficacy.
Extended Release tablet of Antipsychotic drug were prepared using
varying ratios of drug and polymers were selected for the study.
After fixing the ratio of drug and polymer to control the release
of drug up to desired time, the release rates were modulated by
combination of two different rates controlling material. The effect
of polymer concentration and channelizer concentration were
studied. Drug release was observed upto 24 hrs.
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