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Role of Capsaicin in Oxidative Stress and Cancer (Hardcover, 2013 ed.)
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Role of Capsaicin in Oxidative Stress and Cancer (Hardcover, 2013 ed.)
Series: Diet and Cancer, 3
Expected to ship within 12 - 17 working days
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Capsaicin is a principal pungent ingredient of red chili peppers,
first isolated in the early nineteenth century by Christian
Friedrich Bucholz. Widely consumed as a spice in South Asia and
Latin America, Capsaicin has been used to treat pain and
inflammation associated with a variety of diseases, including
rheumatoid arthritis, diabetic neuropathy, post-masectomy pain,
cluster headaches, and herpes zoster. Although recent studies have
evaluated capsaicin as a novel anti-cancer agent, and mechanisms of
capsaicin in preventing cancer have been described sporadically,
the literature lacks a comprehensive review of capsaicin as a
chemo-preventive agent. Role of Capsaicin in Oxidative Stress and
Cancer offers a thorough exploration of the preventive and
therapeutic effects of capsaicin in cancer models such as melanoma,
pancreatic cancer, colon cancer, gastric cancer, breast cancer,
prostate cancer, skin cancer, lung cancer, multiple myeloma and
glioma. The contributors, all internationally recognized
researchers, identify various molecular and cellular targets of
capsaicin, and show the critical role of mitochondria in
capsaicin-mediated therapeutic effects. Readers will learn how
capsaicin prevents or may treat cancer, how different cells respond
to capsaicin, how environmental carcinogen-induced carcinogenesis
can be prevented by capsaicin and the mechanism of oxidative stress
caused by capsaicin. This book will benefit medical students,
oncologists and cancer researchers everywhere.
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