Interventional cardiologists have quickly replaced bare metal
stents with intravascular drug-eluting stents (DES) for treating
and preventing restenosis, largely on the basis of empirical
evidence that shows profound reduction in angiographic and clinical
restenosis. A critical reassessment of the published evidence,
however, suggests that the putative superiority of intravascular
drug-eluting stents is founded on questionable premises, including
overestimation of restenosis benefit, underestimation of the risk
for stent thrombosis, overreliance on "soft" rather than "hard"
outcomes and the attendant overestimation of cost-effectiveness.
Because the long-term incremental risks, benefits, and costs of
drug-eluting stents have not yet been optimally evaluated in a
broad spectrum of patient and lesion cohorts, the rational role of
these devices in clinical management warrants reappraisal. This
book will provide a brief overview of the development of
drug-eluting stents from the laboratory bench to their
investigation in clinical trials and their clinical use.
General
Imprint: |
Lap Lambert Academic Publishing
|
Country of origin: |
Germany |
Release date: |
July 2012 |
First published: |
July 2012 |
Authors: |
Sanjay Patel
• Maulik Patel
|
Dimensions: |
229 x 152 x 7mm (L x W x T) |
Format: |
Paperback - Trade
|
Pages: |
124 |
ISBN-13: |
978-3-659-19582-2 |
Categories: |
Books >
Medicine >
General issues >
General
|
LSN: |
3-659-19582-0 |
Barcode: |
9783659195822 |
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