Lung is the respiratory machinery of the body, which plays an
outstanding array of critical functions in sustenance of the body.
It's often affected by a multitude of drugs, all of which rest a
burden on this vital organ that can culminate in various lung
ailments. The most frequent and imperative obstacle in the
bleomycin therapy is the Pulmonary toxicity. Pulmonary fibrosis
(pneumopathy) is characterized by an increase in lung matrix and
alterations in the numbers and spatial relationships of lung
parenchymal cells. The increase in matrix results from a
proliferation and activation of fibroblasts with increased
production and deposition of matrix macromolecules at sites of lung
injury. In this context, phyllanthus acidus is well known for its
exploitation as an indigenous remedy in many lung, liver ailments.
Thus, the present study was embarked upon in an endeavor to explore
the salubrious role of phyllanthus acidus against the pulmonary
repercussions provoked by bleomycin in a rat model.In this present
study clearly suggest that the administration of Phyanthus acidus
cure the Bleomycin induced pulmonary fibrosis.
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