Metabolic syndrome is a set of risk factors that includes:
abdominal obesity, a decreased ability to process glucose (insulin
resistance), dyslipidemia (unhealthy lipid levels), and
hypertension. Patients who have this syndrome have been shown to be
at an increased risk of developing cardiovascular disease and/or
type 2 diabetes. Metabolic syndrome is a common condition that goes
by many names (dysmetabolic syndrome, syndrome X, insulin
resistance syndrome, obesity syndrome, and Reaven's syndrome).
This is the first book to fully explain the relationships between
psychiatric illness, Metabolic Syndrome, diet, sleep, exercise,
medications, and lifestyle choices. Metabolic Syndrome is a major
risk factor in Major Depression, Alzheimer's Disease, Sleep
Disorders, Sexual Dysfunction, Fibromyalgia, and several other
illnesses of psychiatric significance. Conversely, some psychiatric
illnesses tend to predispose patients to Metabolic Syndrome. Of
further interest is the fact that some of the medications used in
the treatment of psychiatric illnesses have been found to cause or
exacerbate Metabolic Syndrome.
The author here provides basic information about what genetic
predispositions, medical conditions, and lifestyle choices make
Metabolic Syndrome more likely to occur. Among the contributing
factors that are discussed are genetics, habitual intake of high
glycemic index carbohydrates, fructose, saturated fats, trans fatty
acids, vitamins, micronutrients, obesity, smoking, and lack of
exercise.
The author describes the actual mechanisms by which Metabolic
Syndrome progresses and causes damage in the body, including the
action of insulin and the pathophysiology of insulin resistance.
Details are provided on what occurs in the liver, pancreas, muscle,
fat cells, and immune system as Metabolic Syndrome progresses. New
findings are presented on fat cells, including the fact that they
are beginning to be considered as endocrine cells. There is a
substantive discussion of leptin, which is one of the important
adipocytokines. Also carbohydrate, 'bad fats', inflammation,
oxidative damage, over-stimulation of the 'fight or flight' system,
and high levels of the stress hormone cortisol can actually cause
the manifestations of Metabolic Syndrome. These explanations set
the stage for an explanation of the inter-relationships between
Metabolic Syndrome, psychiatric illness, dementia and effects of
not only diet and life choices, but also the effects of psychiatric
medications.
Finally, there is an important and unique section on the
relationship between Metabolic Syndrome and various psychiatric
illnesses, and how they exacerbate each other. The significance of
Metabolic Syndrome in Major Depression, Bipolar Affective Disorder,
Schizophrenia, fibromyalgia and Polycystic Ovary Disease is vast
and it is important to realise the effects of psychiatric
medications on Metabolic Syndrome. The author discusses
antidepressants, mood stabilizers and the new atypical
antipsychotics. There are dramatic differences among medications in
the way they affect Metabolic Syndrome and pharmaceutical companies
will want to promote patient awareness with this book.
* Provides an understanding of Metabolic Syndrome and how this
syndrome is a major risk factor in depression, Alzheimer's Disease,
Sleep Disorders, Sexual Dysfunction, and other illnesses of
psychiatric significance.
* Places specific emphasis on the connection of Metabolic Syndrome
with Psychiatric illnesses, and how these conditions exacerbate
each other.
* Discusses the actual mechanisms by which Metabolic Syndrome
progresses and causes damage to the body.
* Explores the relationship between Major Depression, Heart Disease
and Metabolic Syndrome.
* Includes supplementary section which discusses and critiques many
current dietary supplements that are thought to be helpful for
Metabolic Syndrome.
* Discusses the roles of diet, genetics and supplements in managing
Metabolic Syndrome.
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