Epigenetics and Human Reproduction (Hardcover, 2011 Ed.)

Epigenetics is a rapidly expanding field in medical and biological research which concerns heritable traits that are not attributable to changes in the DNA sequence. Epigenetic mechanisms play key roles in many biological processes, and it has become clear that their disruption can gives rise to diverse pathologies in humans. Edited by preeminent experts, Sophie Rousseaux and Saadi Khochbin, this volume in the Epigenetics and Human Health' series discusses the role of epigenetics in human reproduction. The book presents epigenetic transitions that are important at defined stages of gametogenesis and during meiosis. Several of the sixteen chapters written by experts in the field cover fundamental concepts discovered through cellular and biochemical work and from research on animal models. In other chapters, key examples are provided of how disruption of these mechanisms affects germ cell development and fertility, and contributes to the germinal cancers. Finally, the book discusses how in vitro manipulation and culture in assisted reproduction can epigenetically perturb germ cells, and how this can trigger disease phenotypes in the next generation. Conceived towards advanced students, medical professionals and research scientists, this is the first comprehensive textbook on this topic that will serve as a valuable reference during the years to come.

General

Imprint:	Springer-Verlag
Country of origin:	Germany
Series:	Epigenetics and Human Health
Release date:	November 2010
First published:	2011
Editors:	Sophie Rousseaux • Saadi Khochbin
Dimensions:	235 x 155 x 31mm (L x W x T)
Format:	Hardcover - Cloth over boards
Pages:	372
Edition:	2011 Ed.
ISBN-13:	978-3-642-14772-2
Categories:	Books > Medicine > Pre-clinical medicine: basic sciences > Medical genetics Books > Medicine > Pre-clinical medicine: basic sciences > Human reproduction, growth & development > Reproductive medicine > General
LSN:	3-642-14772-0
Barcode:	9783642147722

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