Proteinkinase Inhibitors (Paperback, 1st ed. 2021)

This book reviews the principles of design and examples of successful implementation of proteinkinase inhibitors (PKI), and offers a comprehensive and authoritative overview of the history and latest developments in the field. Chapters written by experts from industry and academia cover the function, structure and topology of Proteinkinases, molecular modelling, disclose how to achieve high level of selectivity for kinase inhibitors, and exploit kinase inhibitors for cancer treatment. Particular attention is given to Inhibitors of c-Jun N-terminal kinase 3, and to covalent Janus Kinase 3 Inhibitors. A case study on Receptor Tyrosine Kinases EGFR, VEGFR, PDGFR is also presented in this book. Given its breath, this book will appeal to medicinal chemists, students, researchers and professionals alike.

General

Imprint:	Springer Nature Switzerland AG
Country of origin:	Switzerland
Series:	Topics in Medicinal Chemistry, 36
Release date:	March 2022
First published:	2021
Editors:	Stefan Laufer
Dimensions:	235 x 155mm (L x W)
Format:	Paperback
Pages:	256
Edition:	1st ed. 2021
ISBN-13:	978-3-03-068182-1
Categories:	Books > Science & Mathematics > Biology, life sciences > Biochemistry > Proteins Books > Professional & Technical > Industrial chemistry & manufacturing technologies > Industrial chemistry > Pharmaceutical technology
LSN:	3-03-068182-3
Barcode:	9783030681821

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