Biochemical tests of fetal well-being ('placental function tests')
have been part of routine obstetric practice for more than twenty
years. This book provides an overview of the current status of
these tests - the physiological basis for their use, and their
advantages and limitations in clinical practice. Considerable
attention is given to interpretation, a subject which in the past
has led to much confusion both in the scientific literature and in
the minds of clinicians. Recent advances are described in detail,
in particular the discovery of a whole new generation of placental
products some of which offer great promise in the prediction of
conditions, such as placental abruption and premature labour, which
cannot be identified by any other current parameters. Finally, a
set of clear recommendations is put forward for the choice of test
in most of the common complications of both early and late
pregnancy. The emphasis throughout is on how the basic biology of
fetoplacental products dictates their use and interpretation in
pathological conditions.
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