Therapeutic breakthroughs in medicine are usually accompanied by a
wealth of data. Often they result in a change of disease treatment
paradigms. Tacrolimus ointment is the first in the new class of
steroid-free Topical Immunomodulators (TIMs), and as such
represents the first true breakthrough since the introduction of
topical steroids more than 50 years ago for the treatment of T-cell
mediated inflammatory skin diseases such as atopic dermatitis. This
book gives an easy-to-read overview of the discovery and the
development of Tacrolimus ointment for the treatment of atopic
dermatitis. Summarising the largest clinical trial program ever
conducted in dermatology for a new treatment with more than 13000
patients, it offers a detailed insight into the efficacy and safety
profile of Tacrolimus ointment. Based on this large body of data
and extensive personal experience, the authors offer practical and
hands-on guidance for the physician as to when and how to use
Tacrolimus ointment in daily practice.
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