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Studies on Renal Disorders (Paperback, Softcover reprint of the original 1st ed. 2011) Loot Price: R6,695
Discovery Miles 66 950
Studies on Renal Disorders (Paperback, Softcover reprint of the original 1st ed. 2011): Toshio Miyata, Kai-Uwe Eckardt, Masaomi...

Studies on Renal Disorders (Paperback, Softcover reprint of the original 1st ed. 2011)

Toshio Miyata, Kai-Uwe Eckardt, Masaomi Nangaku

Series: Oxidative Stress in Applied Basic Research and Clinical Practice

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Loot Price R6,695 Discovery Miles 66 950 | Repayment Terms: R627 pm x 12*

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Conditions such as oxidative stress and hypoxia, which have a generalized impact on the oxygen metabolism, have been implicated in the genesis of kidney disease. This means that deepening our understanding of the pathobiology of oxygen metabolism in such diseases could be a fruitful path towards tangible clinical benefits. Studies in Renal Disorder collects reviews from leading researchers and clinical scientists working in exactly this field, providing an overview of the latest advances. The causal role of impaired oxygen metabolism in kidney disease has numerous clinical implications. It affects our understanding of the therapeutic benefits accruing from anti-hypertensive agents; the way we control hyperglycemia/hyperinsulinemia and hyperlipidemia; and our use of dietary approaches to the correction of obesity. The defensive mechanisms against oxidative stress, such as the Nrf2-Keap1 system, and hypoxia, such as the PHD-HIF system, have recently been explored in various cells, including kidney cells. These mechanisms include intracellular sensors for oxidative stress and hypoxia. This means that novel approaches targeting these sensors may offer clinical benefits in kidney disease in which oxidative stress and/or hypoxia is a final, common pathway.

General

Imprint: HumanaPress
Country of origin: United States
Series: Oxidative Stress in Applied Basic Research and Clinical Practice
Release date: August 2016
First published: 2011
Editors: Toshio Miyata • Kai-Uwe Eckardt • Masaomi Nangaku
Dimensions: 235 x 155 x 41mm (L x W x T)
Format: Paperback
Pages: 786
Edition: Softcover reprint of the original 1st ed. 2011
ISBN-13: 978-1-4939-5805-4
Categories: Books > Medicine > Clinical & internal medicine > Renal medicine > General
Books > Science & Mathematics > Biology, life sciences > Cellular biology > General
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LSN: 1-4939-5805-4
Barcode: 9781493958054

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