Frovatriptan is latest molecule in category of triptans, used for
migraine therapy. In spite of having great potency and tremendously
long half life, this molecule is not used as first line therapy for
migraine treatment because of its pharmacokinetic limitations.
Preset work is an attempt to surpass the limitations associated
with this molecule by delivering it through orotransmucosal route.
orotransmucosal route will fasten its onset of action and will
increase its bioavailability to atleast 53 %.Also, Present work
have the potential to decrease the overall cost of migraine therapy
and was designed after considering the complications related to
acute migraine attack.
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