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Nuclear-Cytoplasmic Transport (Hardcover, 1st ed. 2018)
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Nuclear-Cytoplasmic Transport (Hardcover, 1st ed. 2018)
Series: Nucleic Acids and Molecular Biology, 33
Expected to ship within 10 - 15 working days
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Dysfunction of nuclear-cytoplasmic transport systems has been
associated with many human diseases. Thus, understanding of how
functional this transport system maintains, or through dysfunction
fails to maintain remains the core question in cell biology. In
eukaryotic cells, the nuclear envelope (NE) separates the genetic
transcription in the nucleus from the translational machinery in
the cytoplasm. Thousands of nuclear pore complexes (NPCs) embedded
on the NE selectively mediate the bidirectional trafficking of
macromolecules such as RNAs and proteins between these two cellular
compartments. In this book, the authors integrate recent progress
on the structure of NPC and the mechanism of nuclear-cytoplasmic
transport system in vitro and in vivo.
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