A constructive evaluation of the most significant developments in
liquid chromatography-mass spectrometry (LC-MS) and its uses for
quantitative bioanalysis and characterization for a diverse range
of disciplines, Liquid Chromatography-Mass Spectrometry, Third
Edition offers a well-rounded coverage of the latest technological
developments and applications.
As the technology itself has matured into a reliable analytical
method over the last 15 years, the most exciting developments occur
in LC-MS augments research into new applications. This edition
places a stronger emphasis than previous editions on the impact of
LC-MS methods, dedicating two-thirds of the text to small-molecule
and biomolecular applications such as proteomics, pharmaceutical
drug discovery and development, biochemistry, clinical analysis,
environmental studies, and natural products research. Supported by
the most relevant literature available, each chapter examines how
the strategies, technologies, and recent advances-from sample
pretreatment to data processing-in LC-MS helped to shape these
disciplines.
Featuring new chapters and extensive revisions throughout the
book, Liquid Chromatography-Mass Spectrometry, Third Edition
continues to provide scientists with a definitive guide and
reference to the most important principles, strategies, and
experimental precedents for applying LC-MS to their research.
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