Mobile Genetic Elements (Paperback, Softcover reprint of hardcover 1st ed. 2004)

Mobile Genetic Elements: Protocols and Genomic Applications brings together a wide array of transposon-based protocols and stategies for studying genome structure, function, and evolution into a highly practical, single-source volume. Such transposable element (TE)-derived techniques have been applied succe- fully for a variety of purposes ranging from mutagenesis, gene silencing, transgenesis, and their use as polymorphic marker systems. To our knowledge no such synthesis has been presented before. Chapters 2-4 provide a series of DNA hybridization techniques for anal- ing the distribution and dynamics of mobile DNAs at the hosts' genomic level. With the current revolution in genomics and the availability of complete genome sequences, computational analyses provide an extremely powerful tool for i- lating and investigating TEs at the in silico level (Chapter 5). For the analyses of transpositional mechanisms at the biochemical level Chapter 6 provides a detailed protocol for LTR retrotransposons in heterologous host systems. Ch- ters 7-10 are focused on TE-based mutagenesis protocols for studying gene functions in a broad range of organisms. Based on their ubiquitous nature and their activity in creating genomic diversity by integrating novel DNA segments into genomes, TEs provide highly informative sets of polymorphic markers (Chapters 11-13). Finally, the last two chapters are dedicated to their technical applications during transgenesis in arthropods and vertebrates.

General

Imprint:	HumanaPress
Country of origin:	United States
Series:	Methods in Molecular Biology, 260
Release date:	November 2010
First published:	2004
Editors:	Wolfgang J. Miller • Pierre Capy
Dimensions:	229 x 152 x 17mm (L x W x T)
Format:	Paperback
Pages:	292
Edition:	Softcover reprint of hardcover 1st ed. 2004
ISBN-13:	978-1-61737-301-5
Categories:	Books > Medicine > Pre-clinical medicine: basic sciences > Medical genetics Promotions
LSN:	1-61737-301-X
Barcode:	9781617373015

Is the information for this product incomplete, wrong or inappropriate? Let us know about it.

Does this product have an incorrect or missing image? Send us a new image.

Is this product missing categories? Add more categories.

Review This Product

No reviews yet - be the first to create one!