Brahmi ghrita was an important formulation used for treatment of
mental disorders mentioned in Ayurveda system of medicine (one of
the oldest medical system).It contain Bacopa monnieri, Convolvulus
pluricaulis, Saussurea lappa, Acorus calamus and old clarified
butter. It was prepared by one of unique pharmaceutical process
mentioned in Ayurveda i.e. Sneha kalpana. Pharmaceutical and
analytical standardization of it was done as per standard protocol
mentioned in Ayurveda and tried to used modern scientific parameter
for it. It pharmacological activity like nontropical and anti
amnesic activity against scopolamine was evaluated by Elevated maze
plus, Passive avoidance and active avoidance models. it was found
that Brahmi Ghrita have significant positive activity in all
models. All ingredient of it have potent effect on Nontropical and
anti amnesic activity except Saussurea lappa which has potent anti
inflammatory activity. Action of Brahmi Ghrita may be due to
synergistic activity of all ingredient used in it.
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