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The Greek Tyrants
A. Andrewes
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R2,681
Discovery Miles 26 810
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Ships in 12 - 17 working days
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First Published in 1956 The Greek Tyrants is concerned primarily
with an early period of Greek history, when the aristocracies which
ruled in the eighth and seventh centuries were losing control of
their cities and were very often overthrown by a tyranny, which in
its turn gave way to the oligarchies and democracies of the
classical period. The tyrants who seized power from time to time in
various cities of Greece are analogous to the dictators of our own
day and represented for the Greeks a political problem which is
still topical: whether it is ever advantageous for a State to
concentrate power in the hands of an individual. Those early
tyrannies are an important phase of Greek political development:
the author discusses here the various military, economic,
political, and social factors of the situation which produce them.
The book thus forms an introduction to the central period of Greek
political history and will be of interest to scholars and
researchers of political thought, ancient history, and Greek
philosophy.
Turn back the clock with History Comics! In this graphic novel,
experience the Stonewall Riots firsthand and meet iconic activists
like Marsha P. Johnson and Sylvia Rivera. Three teenagers--Natalia,
Jax, and Rashad--are magically transported from their modern lives
to the legendary Stonewall Inn in the summer of 1969. Escorted by
Natalia's eccentric abuela (and her pet cockatiel, Rocky), the
friends experience the police raid firsthand and are thrown into
the infamous riots that made the struggle for LGBTQ rights
front-page news.
This unique volume traces the critically important pathway by which
a "molecule" becomes an "anticancer agent. " The recognition
following World War I that the administration of toxic chemicals
such as nitrogen mustards in a controlled manner could shrink
malignant tumor masses for relatively substantial periods of time
gave great impetus to the search for molecules that would be lethal
to specific cancer cells. Weare still actively engaged in that
search today. The question is how to discover these "anticancer"
molecules. Anticancer Drug Development Guide: Preclinical
Screening, Clinical Trials, and Approval, Second Edition describes
the evolution to the present of preclinical screening methods. The
National Cancer Institute's high-throughput, in vitro
disease-specific screen with 60 or more human tumor cell lines is
used to search for molecules with novel mechanisms of action or
activity against specific phenotypes. The Human Tumor
Colony-Forming Assay (HTCA) uses fresh tumor biopsies as sources of
cells that more nearly resemble the human disease. There is no
doubt that the greatest successes of traditional chemotherapy have
been in the leukemias and lymphomas. Since the earliest widely used
in vivo drug screening models were the murine L 1210 and P388
leukemias, the community came to assume that these murine tumor
models were appropriate to the discovery of "antileukemia" agents,
but that other tumor models would be needed to discover drugs
active against solid tumors.
Author John A. Andrews, son of the Caribbean soil, penetrates
inside the belly of the underground. In an environment saturated
with corruption, deception, duplicity, deceit, and inequities of
all kinds, Andrews conceives an international, greed driven fiasco,
embedded within the drug epidemic. Jamaican born, Drug Enforcement
Agent "Rude Boy," is confronted with a massive impasse as three
high ranking members of the Dragon Drug Cartel once assumed dead
re-appear. Allied with the notorious Johnny "Too Bad," they return
in an International face-off. Could Rude Buay survive this
politically disturbing debacle?
This unique volume traces the critically important pathway by which
a "molecule" becomes an "anticancer agent. " The recognition
following World War I that the administration of toxic chemicals
such as nitrogen mustards in a controlled manner could shrink
malignant tumor masses for relatively substantial periods of time
gave great impetus to the search for molecules that would be lethal
to specific cancer cells. Weare still actively engaged in that
search today. The question is how to discover these "anticancer"
molecules. Anticancer Drug Development Guide: Preclinical
Screening, Clinical Trials, and Approval, Second Edition describes
the evolution to the present of preclinical screening methods. The
National Cancer Institute's high-throughput, in vitro
disease-specific screen with 60 or more human tumor cell lines is
used to search for molecules with novel mechanisms of action or
activity against specific phenotypes. The Human Tumor
Colony-Forming Assay (HTCA) uses fresh tumor biopsies as sources of
cells that more nearly resemble the human disease. There is no
doubt that the greatest successes of traditional chemotherapy have
been in the leukemias and lymphomas. Since the earliest widely used
in vivo drug screening models were the murine L 1210 and P388
leukemias, the community came to assume that these murine tumor
models were appropriate to the discovery of "antileukemia" agents,
but that other tumor models would be needed to discover drugs
active against solid tumors.
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A Quick & Easy Bundle (Paperback)
Archie Bongiovanni, Tristan Jimerson, Jules Zuckerberg, Mady G, A. Andrews, …
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R923
Discovery Miles 9 230
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Ships in 12 - 17 working days
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