Thirty years after the Vietnam War, three soldiers collaborate with three short stories each to create

Mathematical and computational biology is playing an increasingly important role in the biological sciences. This science brings forward unique challenges, many of which are, at the moment, beyond the theoretical techniques available. Developmental biology, due to its complexity, has lagged somewhat behind its sister disciplines (such as molecular biology and population biology) in making use of quantitative modeling to further biological understanding. This volume comprises work that is among the best developmental modeling available and we feel it will do much to remedy this situation.
This book is aimed at all those with an interest in the interdisciplinary field of computer and mathematical modeling of multi-cellular and developmental systems. It is also a goal of the Editors to attract more developmental biologists to consider integrating modeling components into their research. Most importantly, this book is intended to serve as a portal into this research area for younger scientists - especially graduate students and post-docs, from both biological and quantitative backgrounds.
* Articles written by leading exponents in the field
* Provides techniques to address multiscale modelling
* Coverage includes a wide spectrum of modeling approaches
* Includes descriptions of the most recent advances in the field

We were motivated to edit this book when we began to hear stories of exceptional students who were struggling with reading, writing, or math, but who could solve seemingly any problem with computers, or build the most intricate structures with Legos, or could draw beautiful pictures, or could tell the most creative stories but ended up in tears when asked to write it out. How is it possible to have so much talent in some areas and yet to appear to have a disability in another? What resources are available for these students? How can we ensure that these students' abilities are nurtured and developed? Our goal in this book is to provide ideas and possibly even tentative answers for educators and to stimulate more questions to be answered by researchers. We have ourselves been addressing related questions for some time. Our group at the PACE Center at Yale has explored the developmentof abilities, competencies and expertise that allow people to be successful in life. Through this work, we have collaborated with school districts and other educators and researchers across the country to expand the notion ofwhat is traditionally thought ofas intelligence. We use the conceptofsuccessful intelligence to allow for the possibility that the skills traditionally taught in school are not the only ones, and often not even the most important ones, that allow people to be successful in the world.

This volume reviews the evolution of information regarding the epidemiology of DCIS and its modes of detection, as well as treatment options as a function of both clinical trial data and ongoing investigational therapeutic prospects. Several of the challenging and clinically-relevant scenarios of DCIS that appear in daily practice is discussed, including the difficulties of distinguishing "true" DCIS from borderline patterns of other breast diseases and the therapeutic implications of differentiating these various diagnoses. Particular attention is paid to pathologic evaluation of DCIS, including histologic patterns and the importance of margin evaluation/margin control. The text also explores the data regarding DCIS in medical research in hereditary susceptibility for breast cancer and race/ethnicity-associated disparities in breast cancer. Written by experts in the field, Ductal Carcinoma In Situ and Microinvasive/Borderline Breast Cancer is a comprehensive, state-of-the art review of the field, and serves as a valuable resource for clinicians, surgeons and researchers with an interest in breast cancer.

The author's of the award-winning Emotional Labor now go inside the stressful world of suicide, rape, and domestic hotline workers, EMTs, triage nurses, and agency/deparment spokespersons, to provide powerful insights into how emotional labor is actually exerted by public servants who face the gravest challenges.

The author's of the award-winning Emotional Labor now go inside the stressful world of suicide, rape, and domestic hotline workers, EMTs, triage nurses, and agency/deparment spokespersons, to provide powerful insights into how emotional labor is actually exerted by public servants who face the gravest challenges.

This volume reviews the evolution of information regarding the epidemiology of DCIS and its modes of detection, as well as treatment options as a function of both clinical trial data and ongoing investigational therapeutic prospects. Several of the challenging and clinically-relevant scenarios of DCIS that appear in daily practice is discussed, including the difficulties of distinguishing "true" DCIS from borderline patterns of other breast diseases and the therapeutic implications of differentiating these various diagnoses. Particular attention is paid to pathologic evaluation of DCIS, including histologic patterns and the importance of margin evaluation/margin control. The text also explores the data regarding DCIS in medical research in hereditary susceptibility for breast cancer and race/ethnicity-associated disparities in breast cancer. Written by experts in the field, Ductal Carcinoma In Situ and Microinvasive/Borderline Breast Cancer is a comprehensive, state-of-the art review of the field, and serves as a valuable resource for clinicians, surgeons and researchers with an interest in breast cancer.

A poignant tribute to the life of Matthew Shepard and his legacy in the fight for LGBTQ+ rights, published on the 25th anniversary of the formation of the Matthew Shepard FoundationOn the night of October 6, 1998, in Laramie, Wyoming, Matthew Wayne Shepard (1976–1998) was brutally killed solely because he was gay. It was a shocking murder that was nationally covered in the media, and it became a rallying cry for the LGBTQ+ rights movement. In 2009, the Matthew Shepard and James Byrd Jr. Hate Crimes Prevention Act was signed by President Barack Obama, expanding the federal hate crime law to include crimes motivated by a victim’s actual or perceived gender, sexual orientation, gender identity, or disability.With a foreword by Jason Collins—the first openly gay, active player in the NBA—and written by Lesléa Newman—author of the Stonewall Honor–winning novel-in-verse October Mourning: A Song for Matthew Shepard, and a friend of the Shepard family—Always Matt is an emotional yet ultimately hopeful look at the progress that’s been made, as well as the work that still continues, in advocating for the dignity and equality of all people. Without shying away from the pain and tragedy of his death, moving, lyrical prose and minimalist line drawings present a celebration of his incredible life. Twenty-five years after the formation of the Matthew Shepard Foundation, which dedicates its mission to erasing hate, Matthew’s story still resonates for those who lived through it, and remains a vital piece of LGBTQ+ history for younger generations to learn.

We were motivated to edit this book when we began to hear stories of exceptional students who were struggling with reading, writing, or math, but who could solve seemingly any problem with computers, or build the most intricate structures with Legos, or could draw beautiful pictures, or could tell the most creative stories but ended up in tears when asked to write it out. How is it possible to have so much talent in some areas and yet to appear to have a disability in another? What resources are available for these students? How can we ensure that these students' abilities are nurtured and developed? Our goal in this book is to provide ideas and possibly even tentative answers for educators and to stimulate more questions to be answered by researchers. We have ourselves been addressing related questions for some time. Our group at the PACE Center at Yale has explored the developmentof abilities, competencies and expertise that allow people to be successful in life. Through this work, we have collaborated with school districts and other educators and researchers across the country to expand the notion ofwhat is traditionally thought ofas intelligence. We use the conceptofsuccessful intelligence to allow for the possibility that the skills traditionally taught in school are not the only ones, and often not even the most important ones, that allow people to be successful in the world.

Most public service jobs require interpersonal contact that is either face-to-face or voice-to-voice - relational work that goes beyond testable job skills but is essential for job completion. This unique book focuses on this emotional labor and what it takes to perform it.The authors weave a powerful narrative of stories from the trenches gleaned through interviews, focus groups, and survey data. They go beyond the veneer of service delivery to the real, live, person-to-person interactions that give meaning to public service.For anyone who has ever felt apathetic toward government work, the words of caseworkers, investigators, administrators, attorneys, correctional staff, and 9/11 call-takers all show the human dimension of bureaucratic work and underscore what it means to work "with feeling."

Most public service jobs require interpersonal contact that is either face-to-face or voice-to-voice - relational work that goes beyond testable job skills but is essential for job completion. This unique book focuses on this emotional labor and what it takes to perform it.The authors weave a powerful narrative of stories from the trenches gleaned through interviews, focus groups, and survey data. They go beyond the veneer of service delivery to the real, live, person-to-person interactions that give meaning to public service.For anyone who has ever felt apathetic toward government work, the words of caseworkers, investigators, administrators, attorneys, correctional staff, and 9/11 call-takers all show the human dimension of bureaucratic work and underscore what it means to work "with feeling."

Grasslands are the most extensive terrestrial biome on Earth and are critically important for forage, biodiversity, and ecosystem services. This book brings together an international team of researchers to review scientific knowledge of the effects of climate change on world grasslands, a process we are only just starting to understand. Part I assesses how climate change will impact on the distribution of grasslands, as well as production, biogeochemical cycling and ecosystem services. Part II considers the consequences for the spread of invasive species, demographic change, trophic-level relationships, soil biota, and evolutionary change within grassland biodiversity. Part III proposes how ecologists can respond to climate change effects, focusing on grazing systems, cultural ecology, range management, and restoration. The concluding chapter sets grasslands in the context of the Anthropocene era and identifies the vital research and conservation needs for grassland ecosystems to remain environmentally sustainable under climate change.

Imagine that you are an environmentalist who passionately believes that it is wrong to drill for oil in the Arctic National Wildlife Refuge. How do you convince someone that a decision to drill is wrong? Debates about the environment and how humans ought to treat it have gone on for decades, yet arguments in favor of preserving biodiversity often lack empirical substance or are philosophically naive, making them far less effective than they could be. This book critically examines arguments that are commonly offered in support of biodiversity conservation. The authors adopt a skeptical viewpoint to thoroughly test the strength of each argument and, by demonstrating how scientific evidence can be integrated with philosophical reasoning, they help environmentalists to better engage with public debate and judiciously inform public policy. This interdisciplinary and accessible book is essential reading for anyone who engages in discussions about the value of biodiversity conservation.

Imagine that you are an environmentalist who passionately believes that it is wrong to drill for oil in the Arctic National Wildlife Refuge. How do you convince someone that a decision to drill is wrong? Debates about the environment and how humans ought to treat it have gone on for decades, yet arguments in favor of preserving biodiversity often lack empirical substance or are philosophically naive, making them far less effective than they could be. This book critically examines arguments that are commonly offered in support of biodiversity conservation. The authors adopt a skeptical viewpoint to thoroughly test the strength of each argument and, by demonstrating how scientific evidence can be integrated with philosophical reasoning, they help environmentalists to better engage with public debate and judiciously inform public policy. This interdisciplinary and accessible book is essential reading for anyone who engages in discussions about the value of biodiversity conservation.

During development cells and tissues undergo changes in pattern and form that employ a wider range of physical mechanisms than at any other time in an organism's life. This book shows how physics can be used to analyze these biological phenomena. Written to be accessible to both biologists and physicists, major stages and components of the biological development process are introduced and then analyzed from the viewpoint of physics. The presentation of physical models requires no mathematics beyond basic calculus. Physical concepts introduced include diffusion, viscosity and elasticity, adhesion, dynamical systems, electrical potential, percolation, fractals, reaction-diffusion systems, and cellular automata. With full-color figures throughout, this comprehensive textbook teaches biophysics by application to developmental biology and is suitable for graduate and upper-undergraduate courses in physics and biology.

Grasslands are the most extensive terrestrial biome on Earth and are critically important for forage, biodiversity, and ecosystem services. This book brings together an international team of researchers to review scientific knowledge of the effects of climate change on world grasslands, a process we are only just starting to understand. Part I assesses how climate change will impact on the distribution of grasslands, as well as production, biogeochemical cycling and ecosystem services. Part II considers the consequences for the spread of invasive species, demographic change, trophic-level relationships, soil biota, and evolutionary change within grassland biodiversity. Part III proposes how ecologists can respond to climate change effects, focusing on grazing systems, cultural ecology, range management, and restoration. The concluding chapter sets grasslands in the context of the Anthropocene era and identifies the vital research and conservation needs for grassland ecosystems to remain environmentally sustainable under climate change.