|
Showing 1 - 7 of
7 matches in All Departments
An essential component of inflammation is the migration of
circulating leukocytes from blood into tissues. This process is
characterized by a multistep paradigm of sequential cell adhesion
and activation events that lead to the extravasation of specific
leukocyte subsets to different tissues in health and disease. The
first step of leukocyte extravasation, the rolling of leukocytes,
is primarily mediated by the interactions of selectins and their
ligands. It has recently become evident that fucosyltransferases
are crucial for selectin ligand synthesis, inflammation, and skin
homing. This book provides an in-depth overview of the mechanisms
of leukocyte trafficking and of the molecular mechanisms of
selectin/selectin ligand interactions and discusses options for
pharmacological intervention to treat inflammatory diseases.
An essential component of inflammation is the migration of circulating leukocytes from blood into tissues. This process is characterized by a multistep paradigm of sequential cell adhesion and activation events that lead to the extravasation of specific leukocyte subsets to different tissues in health and disease. The first step of leukocyte extravasation, the rolling of leukocytes, is primarily mediated by the interactions of selectins and their ligands. It has recently become evident that fucosyltransferases are crucial for selectin ligand synthesis, inflammation, and skin homing. This book provides an in-depth overview of the mechanisms of leukocyte trafficking and of the molecular mechanisms of selectin/selectin ligand interactions and discusses options for pharmacological intervention to treat inflammatory diseases.
This scarce antiquarian book is a selection from Kessinger
Publishing's Legacy Reprint Series. Due to its age, it may contain
imperfections such as marks, notations, marginalia and flawed
pages. Because we believe this work is culturally important, we
have made it available as part of our commitment to protecting,
preserving, and promoting the world's literature. Kessinger
Publishing is the place to find hundreds of thousands of rare and
hard-to-find books with something of interest for everyone
|
You may like...
Loot
Nadine Gordimer
Paperback
(2)
R398
R330
Discovery Miles 3 300
|
Email address subscribed successfully.
A activation email has been sent to you.
Please click the link in that email to activate your subscription.