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Leucocyte Trafficking - The Role of Fucosyltransferases and Selectins (Paperback, Softcover reprint of the original 1st ed. 2004) Loot Price: R2,724
Discovery Miles 27 240
Repayment Terms: R255 pm x 12*
Leucocyte Trafficking - The Role of Fucosyltransferases and Selectins (Paperback, Softcover reprint of the original 1st ed....

Leucocyte Trafficking - The Role of Fucosyltransferases and Selectins (Paperback, Softcover reprint of the original 1st ed. 2004)

A.H. Amann, Khusru Asadullah, A Schottelius

Series: Ernst Schering Foundation Symposium Proceedings, 44

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Loot Price R2,724 Discovery Miles 27 240 | Repayment Terms: R255 pm x 12*

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An essential component of inflammation is the migration of circulating leukocytes from blood into tissues. This process is characterized by a multistep paradigm of sequential cell adhesion and activation events that lead to the extravasation of specific leukocyte subsets to different tissues in health and disease. The first step of leukocyte extravasation, the rolling of leukocytes, is primarily mediated by the interactions of selectins and their ligands. It has recently become evident that fucosyltransferases are crucial for selectin ligand synthesis, inflammation, and skin homing. This book provides an in-depth overview of the mechanisms of leukocyte trafficking and of the molecular mechanisms of selectin/selectin ligand interactions and discusses options for pharmacological intervention to treat inflammatory diseases.

General

Imprint: Springer-Verlag
Country of origin: Germany
Series: Ernst Schering Foundation Symposium Proceedings, 44
Release date: February 2013
First published: 2004
Editors: A.H. Amann • Khusru Asadullah • A Schottelius
Dimensions: 210 x 148 x 13mm (L x W x T)
Format: Paperback
Pages: 242
Edition: Softcover reprint of the original 1st ed. 2004
ISBN-13: 978-3-662-05399-7
Categories: Books > Medicine > Clinical & internal medicine > Dermatology
Books > Medicine > General issues > Medical equipment & techniques > Medical research
Books > Medicine > Pre-clinical medicine: basic sciences > Physiology > General
Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology > General
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LSN: 3-662-05399-3
Barcode: 9783662053997

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