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Recent advances in molecular biology have provided new dimensions
in the study of the reproductive system. There has been major
progress in our understanding of the molecular mechanisms of
hormone action in the past few' years. The symposium on "Molecular
Basis of Reproductive Endocrinology" was organized to highlight new
research findings on the regulation of the
hypothalamic-pituitary-gonadal axis. The emphasis of the symposium
was on physiological questions answered by the molecular biology
approach. Studies on the functional relevance of gonadotropin
releasing hormone and LH and FSH gene expression were presented,
together with research on the molecular biology of ovarian and
testicular steroidogenic enzymes and protein hormones. Also,
several novel aspects of hormone gene expression in placental
tissues were reviewed. The symposium was held July 25 to 26, 1991,
immediately prior to the 24th Annual Meeting of the Society for the
Study of Reproduction, on the campus of the University of British
Columbia in Vancouver. Serono Symposia, USA generously financed and
coordinated the meeting. We are indebted to Dr. Bruce K. Burnett
and Dr. L. Lisa Kern for their professional assistance in the
organization of the symposium. We would also like to thank Drs.
Victor Gomel, Basil Ho Yuen, and John Challis, who served as
session moderators. Most of all, we truly appreciate the efforts of
all the invited speakers, poster presenters, and discussants in
making this a memorable event as the largest one-day meeting of the
Serono Symposia USA, series.
Due to the introduction of molecular and cellular biology
approaches, our understanding of ovarian physiology has reached a
new level during the last few years. The present volume provides a
new perspective on the ovary from molecular and cellular to whole
organ levels, from non-mammalian and rodent to human levels and
from paracrine, neuroendocrine and endocrine levels as well. These
papers represent the proceedings of the Ninth Ovarian Workshop
sponsored by Serono Symposia, USA, July 9-11, 1992 in Chapel Hill,
North Carolina.
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