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The objective of this study was to determine the knowledge,
behavior and perception of self-medication practice among the
students of Pharmaceutical sciences from different private and
public Universities of Bangladesh. The study showed that each and
every respondent (n=474) (100%) had knowledge about
self-medication. The most common indications for self medication
were diarrhea (95.15%), fever (94.30%), headache (76.16%), cough
(70.04%), gastric pain (65.82%), allergy (52.32%), vomiting
(45.78%), vitamin deficiency (45.57%), stomachache (40.51%),
constipation (37.13%), insomnia (33.97%), and skin diseases
(29.11%). The major reasons for self medication were non-serious
illness (87.55%), emergency use (79.96%), quick relief (85.86%),
previous experience (83.97%), and unavailability of doctors
(89.87%), advice from the family members / friends (51.90%), and
cost-effectiveness (41.35%). The result showed that self medication
was done mainly by analgesics (65.12%), the drugs acting on GIT
(62.14%), cough suppressants (38.15%), antibiotics (22.86%),
antihistamines (25.67%), and vitamins (25.81%).
We investigated the knowledge and perception about HIV/AIDS among
the University students of Dhaka city in Bangladesh. A total number
of 162 respondents participated in the study. Data were collected
prospectively from different public and private Universities of
Dhaka city in Bangladesh. The study showed that every respondent
heard about HIV/AIDS and their main source of knowledge about
HIV/AIDS was from media (72%). Among the respondents, 64% regularly
donated blood and few of them (38%) were careful during blood
donation. 95% of the respondents (who were drug abusers) did not
share injections or needles for taking drugs of abuse. 97% of the
respondents did not exchanged sex for drugs or money; however, 25%
had physical relation with their sex partners and among them, only
24% used condoms while 57% knew about the use of condom. Only 27%
of the respondents knew about HIV test centers. 90% thought that
HIV/AIDS education will increase awareness about HIV/AIDS. 35% of
the respondents were familiar with condom vendor machines and 28%
of the respondents did not support for condom vendor machines to be
installed in public places in Bangladesh.
Pharmacogenetics is generally regarded as the study of genetic
variation that gives rise to different responses to drugs. It may
be possible to predict therapeutic failures or severe adverse drug
reactions in individual patients by testing for important DNA
sequence variations or polymorphisms in key drug-metabolizing
enzymes, receptors, transporters, etc. In this book, we
characterized methods for genotyping CYP3A4*2, CYP3A4*4, CYP3A4*5,
CYP3A4*6, and CYP3A4*10 alleles among Bangladeshi population in 70
healthy adult unrelated volunteers. Cytochrome P450 3A (CYP3A)
subfamily is responsible for the metabolism of more than 60% drugs
used by the human including clinically important drugs like
nifedipine, cyclosporine, erythromycin, midazolam, triazolam,
digitoxin, lidocaine, and quinine etc. Venous blood samples were
collected from 70 healthy Bangladeshi volunteers. Genomic DNA was
extracted from these blood samples and PCR-RFLP analysis was
employed to genotype important alleles of CYP3A4. CYP3A4*2,
CYP3A4*4, CYP3A4*5, CYP3A4*6, and CYP3A4*10 alleles were found to
be absent in Bangladeshi population, which are common in other
ethnic groups
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