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Metabolic Syndrome is an aggregation of conditions that together
increases the risk of cardiovascular disease in individuals that
would not otherwise be recognized to be at risk. Aim: to assess the
status of high sensitive C reactive protein (hs-CRP) in patients
with Metabolic Syndrome. METHODS: This study is a cross-sectional
study. The patients included in this study were 48 patients (of
both sexes) attending the Diabetic Consultant Clinic during the
period from January, 2010 till the end of September, 2010. The
study included another 50 apparently healthy volunteer that were
comparable to patients group with respect to age and sex and serve
as a control group. They were screened for Metabolic Syndrome
criteria.For the two groups hs-CRP was measured using ELISA kit.
The results: BMI and BP were significantly higher in the MetS than
the control. MetS group had significantly higher (hs-CRP) levels
than control group and significantly higher Lipid profile than the
control group. In conclusion, high sensitive C Reactive Protein can
thus be simple, powerful markers of Metabolic Syndrome.
This is a cross sectional study on 400 cases of diabetes mellitus
who attended the National Diabetic centre/ AL-Mustensyria
university for a period of 6 months. The main factor of metabolic
syndrome was dysglycaemia followed by hypertension, obesity and
dyslipidaemia. Females in this study were more prone to have
metabolic syndrome; Male: Female ratio = 0.5. Those in the age
group 60-69 have the highest frequency of metabolic syndrome. Those
with BMI 30-40 have the highest frequency of metabolic syndrome.
Conclusion: This study concludes that early diagnosis and
aggressive treatment is needed for metabolic syndrome to avoid
cardiovascular complications. This study is important because of
its predictive power for cardiovascular complication and diabetes.
In addition to hypercholesterolaemia and smoking, hypertension, a
chronic disease with many cardiovascular complications, is one of
the major risk factors for cardiac ischemia, and the main risk
factor for cerebrovascular disease. To elucidate the role of
oxidative stress and lipid peroxidation in hypertension and the
effect of different medical therapies on these parameters.The
present study included measurement of serum lipid profile, total
lipid peroxidation and oxidized HDL ( Ox-HDL)in 69 patients aged
30-70 years . They were three groups according to the type of
therapy: atenelol, captopril & no pharmacological
antihypertensives NPAHT. The results were compared with those of 45
apparently healthy controls(age range=30-66 years). The results
showed a significant elevation in serum MDA and the OX.non-HDL %
with a significant reduction in the reduction in the OX.HDL % as
compared to the controls. The disturbance in the oxidant /
antioxidant balance happened despite the treatment and blood
pressure control showing different pictures with different
modalities of treatment, being the best with the captopril.
Preeclampsia is a form of high blood pressure manifested during
pregnancy, it is a common major complication causing significant
morbidity and mortality; however, its etiology is unknown. The
systemic vasculature is a target tissue for sex steroid hormones.
Estrogen, androgen, and progesterone all influence the function and
pathophysiology of the systemic circulation by influencing
endothelial derived nitric-oxide pathway. Evidence suggests that
sex steroids also modulate electrolyte homeostasis, but data on
cation pattern during pregnancy are conflicting. Moreover, the
status of ionized calcium and magnesium during pregnancy and its
complication preeclampsia, and its relation with endothelial
derived nitric-oxide and sex hormones have not been described
adequately. The aim of this study is to demonstrate the pattern of
sex steroids, minerals and electrolytes during preeclampsia with
respect to normal pregnancy, and the correlation of the above
parameters with nitric-oxide pathway. This study shows
thatpreeclamptics (in different gestational age groups) experience
vasospasm, hyperandrogenemia, altered electrolytes and mineral
status, with no difference in sex steroids.
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