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This book is an attempt to indicate to researchers and clinicians a
simple way to approach the complexity of cardiovascular neural
regulation. A conceptual pillar like homeostasis is contrasted with
instability and a continuous interaction of opposing mechanisms
that have negative and positive feedback characteristics, and is
considered to subserve the multitude of patterns pertaining to
physiology. However, in pathophysiological conditions the final
design is most often replaced by largely purposeless neural
mechanisms. The complexity of cardiovascular neural regulation,
reflected by the state of sympathovagal balance, is also assessed
in the frequency domain. Power spectrum analysis of heart rate and
arterial pressure variability, a sophisticated but simply explained
approach, provides an unprecedented tool to evaluate this
interaction in both physiological and pathophysiological
conditions. The elementary characteristics of nonlinear dynamics
are also outlined. Finally, the need for an ethical structure for
science and medicine is analyzed.
This book is an attempt to indicate to researchers and clinicians a
simple way to approach the complexity of cardiovascular neural
regulation. A conceptual pillar like homeostasis is contrasted with
instability and a continuous interaction of opposing mechanisms
that have negative and positive feedback characteristics, and is
considered to subserve the multitude of patterns pertaining to
physiology. However, in pathophysiological conditions the final
design is most often replaced by largely purposeless neural
mechanisms. The complexity of cardiovascular neural regulation,
reflected by the state of sympathovagal balance, is also assessed
in the frequency domain. Power spectrum analysis of heart rate and
arterial pressure variability, a sophisticated but simply explained
approach, provides an unprecedented tool to evaluate this
interaction in both physiological and pathophysiological
conditions. The elementary characteristics of nonlinear dynamics
are also outlined. Finally, the need for an ethical structure for
science and medicine is analyzed.
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