This book presents current research in the study of the causes, management and prognosis in brain damage including the implications for therapeutic intervention in the reorganisation of elementary functions (REF) after brain injury; a reorientation towards fibre tracts damage in amnesia; the use of alkaline comet assay to assess DNA damage and repair in brain damage; responsiveness and prognosis in the severe disorder of consciousness; the pathophysiology, management and prognosis of cerebral radiation necrosis; exercise as a therapeutic approach after brain damage; neuroprotection in experimental cerebral ischemia; and initiation of inflammatory mechanisms in acute brain damage.