Common factors that lead to treatment failure in head and neck cancer are the lack of tumour oxygenation, the accelerated division of cancer cells during treatment, and radioresistance. These tumour-related challenges and possible ways to overcome them are covered in this book, authored by three medical physicists and a clinical oncologist who explain how different radiobiological findings have led to the development of various treatment techniques for head and neck cancer. Novel treatment techniques as supported by current scientific evidence are comprehensively explored, as well as the major challenges that arise in the retreatment of patients who have already undergone a form of radiotherapy for primary head and neck cancer. Features: Uses an interdisciplinary approach, encompassing clinical aspects of radiotherapy, radiation biology, and medical physics Applies content by relating all radiobiological characteristics to their respective clinical implications Explains the radiobiological rationale for all previous and current clinical trials for head and neck cancer

The late John ""Jack"" Fowler was a busy radiation biology researcher and teacher who wrote 581 papers over the last 65 plus years. He also received nearly every honour the medical physics field can bestow. This book sums up the key concepts relating to optimum fractionation in radiation therapy that interested him throughout his life. Just under 100 pages in length, this book is a quick, informative, and enjoyable read.