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Although the available models, whether at the cellular, tissue,
or animal level, do not exactly represent the biology of human
brain tumors, animal models can offer significant insights into
these tumors, providing a better understanding of biological
mechanisms underlying tumor generation, growth, angiogenesis,
invasion, and metastasis. "Animal Models of Brain Tumors" brings
together developments and discoveries in in vivo experimental tumor
research that have provided advances in our understanding of the
cellular and molecular mechanisms involved in the generation,
progression, and clinical outcome of brain neoplasms. Broken into
convenient sections, this thorough volume includes topics such as
animal model insights into human brain neoplasms, the cellular,
molecular, and genetic basis of brain tumors, therapies in the
treatment of malignant glioma, as well as imaging technologies in
animal tumor models, i.e. measuring brain tumor growth and
metabolism. Written for the popular "Neuromethods "series, chapters
include the kind of detailed description and implementation advice
that is essential for achieving successful results.
Authoritative and cutting-edge, "Animal Models of Brain Tumors"
provides the key methods needed to validate, compare, and contrast
the animal model with its proposed human counterpart and further
the understanding of our own serious ailments."
Although the available models, whether at the cellular, tissue, or
animal level, do not exactly represent the biology of human brain
tumors, animal models can offer significant insights into these
tumors, providing a better understanding of biological mechanisms
underlying tumor generation, growth, angiogenesis, invasion, and
metastasis. Animal Models of Brain Tumors brings together
developments and discoveries in "in vivo" experimental tumor
research that have provided advances in our understanding of the
cellular and molecular mechanisms involved in the generation,
progression, and clinical outcome of brain neoplasms. Broken into
convenient sections, this thorough volume includes topics such as
animal model insights into human brain neoplasms, the cellular,
molecular, and genetic basis of brain tumors, therapies in the
treatment of malignant glioma, as well as imaging technologies in
animal tumor models, i.e. measuring brain tumor growth and
metabolism. Written for the popular Neuromethods series, chapters
include the kind of detailed description and implementation advice
that is essential for achieving successful results. Authoritative
and cutting-edge, Animal Models of Brain Tumors provides the key
methods needed to validate, compare, and contrast the animal model
with its proposed human counterpart and further the understanding
of our own serious ailments.
In post-Franco Spain, a re-shaping of notions of the masculine has
been under way for some time. The authors of "Live Flesh"
demonstrate how contemporary Spanish films, during this modern
period, have contributed to this process. They do so by visualizing
the ways in which Spanish men have been abandoning old self images
and adopting new ones, and they explain and explore the complexity
and diversity of these fresh cinematic creations of masculine
identities.
The book's point of focus is Spanish films of the democratic
period, both popular and auteur, made by directors of national and
international prominence, such as Pedro Almodovar, Alejandro
Amenabar, Bigas Luna or Julio Medem, as well as films featuring
acclaimed actors who have contributed to the construction of
contemporary ideas of the masculine in their country, including
Antonio Banderas and Javier Bardem. Using a fresh theoretical
framework, embracing queer and feminist theory and concepts of
nation, race and class, each chapter examines key films that
represent the male body, highlighting notable elements - young,
muscular, homosexual, (dis)abled, foreign and so on - and goes on
to focus on recent case studies from the early 1990s to the
present.
" "
An increasingly transnational Spanish cinema is a most promising
field in which to explore questions of how male bodies are
represented - and mediated - in film. "Live Flesh" more than
fulfils this promise and goes further, to reveal how these
representations have intervened in the Spanish cultural
imagination.
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