Although the available models, whether at the cellular, tissue, or animal level, do not exactly represent the biology of human brain tumors, animal models can offer significant insights into these tumors, providing a better understanding of biological mechanisms underlying tumor generation, growth, angiogenesis, invasion, and metastasis. "Animal Models of Brain Tumors" brings together developments and discoveries in in vivo experimental tumor research that have provided advances in our understanding of the cellular and molecular mechanisms involved in the generation, progression, and clinical outcome of brain neoplasms. Broken into convenient sections, this thorough volume includes topics such as animal model insights into human brain neoplasms, the cellular, molecular, and genetic basis of brain tumors, therapies in the treatment of malignant glioma, as well as imaging technologies in animal tumor models, i.e. measuring brain tumor growth and metabolism. Written for the popular "Neuromethods "series, chapters include the kind of detailed description and implementation advice that is essential for achieving successful results.

Authoritative and cutting-edge, "Animal Models of Brain Tumors" provides the key methods needed to validate, compare, and contrast the animal model with its proposed human counterpart and further the understanding of our own serious ailments."

The Spanish novel in a turbulent century. This collection of studies by eighteen prominent theorists and critics offers a diverse panorama of the modern Spanish novel seen through the prism of Spain's recent political, cultural and ideological history. It considers the development of the novel as a social mirror and as a changing literary form, torn between the tradition of stern realism and the aesthetics of rupture affecting all Western literature from the Avant-Garde to the Postmodern age. While some essays emphasise the Spanish cultural context and canonical writers, others are of a broader nature, grouping lesser-known writers under certain literary tendencies: the metaphysical novel, the urban novel, recuperative accounts of the Civil War, feminine first-person narrations, and the rise of the popular detective, historical, and erotic novels. Three studies address the resurgence of the Catalan, Basque and Galician novel and their departure from a poetics of identity to one of global concerns. Interdisciplinary approaches address the reciprocal impacts of literature and cinema, and the effects of the marketplace on the consumption of fiction are not forgotten. The Companion provides ample bibliographies and a valuable chronology, while all titles and quotations are translated into English. Contributors: Marta E. Altisent, Katarzyna Olga Beilin, Ramon Buckley, Jose F. Colmeiro, Stacey Dolgin Casado, Sebastiaan Faber, David K. Herzberger, Carlos Alex Longhurst, Kathleen N. March, Cristina Martinez-Carazo, Alfredo Martinez Exposito, Nina L. Molinaro, Gonzalo Navajas, Mari Jose Olaziregi, Janet D. Perez, Randolph D. Pope, Josep Miquel Sobrer, H. Rosi Song.

Although the available models, whether at the cellular, tissue, or animal level, do not exactly represent the biology of human brain tumors, animal models can offer significant insights into these tumors, providing a better understanding of biological mechanisms underlying tumor generation, growth, angiogenesis, invasion, and metastasis. Animal Models of Brain Tumors brings together developments and discoveries in "in vivo" experimental tumor research that have provided advances in our understanding of the cellular and molecular mechanisms involved in the generation, progression, and clinical outcome of brain neoplasms. Broken into convenient sections, this thorough volume includes topics such as animal model insights into human brain neoplasms, the cellular, molecular, and genetic basis of brain tumors, therapies in the treatment of malignant glioma, as well as imaging technologies in animal tumor models, i.e. measuring brain tumor growth and metabolism. Written for the popular Neuromethods series, chapters include the kind of detailed description and implementation advice that is essential for achieving successful results. Authoritative and cutting-edge, Animal Models of Brain Tumors provides the key methods needed to validate, compare, and contrast the animal model with its proposed human counterpart and further the understanding of our own serious ailments.