Although the available models, whether at the cellular, tissue,
or animal level, do not exactly represent the biology of human
brain tumors, animal models can offer significant insights into
these tumors, providing a better understanding of biological
mechanisms underlying tumor generation, growth, angiogenesis,
invasion, and metastasis. "Animal Models of Brain Tumors" brings
together developments and discoveries in in vivo experimental tumor
research that have provided advances in our understanding of the
cellular and molecular mechanisms involved in the generation,
progression, and clinical outcome of brain neoplasms. Broken into
convenient sections, this thorough volume includes topics such as
animal model insights into human brain neoplasms, the cellular,
molecular, and genetic basis of brain tumors, therapies in the
treatment of malignant glioma, as well as imaging technologies in
animal tumor models, i.e. measuring brain tumor growth and
metabolism. Written for the popular "Neuromethods "series, chapters
include the kind of detailed description and implementation advice
that is essential for achieving successful results.
Authoritative and cutting-edge, "Animal Models of Brain Tumors"
provides the key methods needed to validate, compare, and contrast
the animal model with its proposed human counterpart and further
the understanding of our own serious ailments."
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