As a physician who personally suffers from depression, Susan J. Noonan draws on her own expertise and empathy to create a guide for people who suffer from the disease. Explaining the basics of mental health-including sleep hygiene, diet and nutrition, exercise, routine and structure, and avoiding isolation - "Managing Your Depression" empowers people to participate in their own care, offering them a better chance of getting, and staying, well. Noonan's depression management strategies draw on the best available educational resources, psychoeducational programs, seminars, expert health care providers, and patient experiences. The book is specifically designed to be highly readable for people who are finding it difficult to focus and concentrate during an episode of depression. Cognitive exercises and daily worksheets help track progress and response to therapy and provide valuable information for making treatment decisions. A relapsing and remitting condition, depression affects nearly 15 percent of people in the United States. "Managing Your Depression" will bring depression management strategies to people who do not have access to mental health programs or who want to learn new skills.

Poor clinical trial designs result in failed studies wasting research funds and limiting the advancement of cures for disorders. Clinical Trial Design Challenges in Mood Disorders outlines classic problems researchers face in designing clinical trials and discusses how best to address them for the most definitive and generalizable results. Traditional trial designs are included as well as novel analytic techniques. The book examines information on high placebo response, the generalizability of studies conducted in the developing world, the duration of maintenance studies, and the application of findings into clinical practice. With representation from contributors throughout the world and from academia, industry, regulatory agencies, and advocacy groups, this book will contribute toward improved clinical trial design and valid, precise, and reliable answers about what works better and faster for patients.

Although antidepressants have helped millions worldwide, a substantial proportion of patients fail to respond or remit. There is little published information available to clinicians for diagnosis and management of treatment-resistant depression, causing them to make difficult decisions regarding treatment options with very limited data. The editors and their internationally distinguished team of contributors have set out to address this problem, giving a critical assessment of all aspects of treatment-resistant depression: causes, epidemiology, comorbidity, evaluation, and treatment. This timely book will be invaluable to clinicians, neuroscientists, researchers, and graduate students.

Grounded in current knowledge about bipolar disorder and its treatment, this book presents an empirically supported therapy program with step-by-step guidelines for implementation. Mindfulness-based cognitive therapy (MBCT) for bipolar disorder is specifically designed for clients who have experienced many mood episodes and who struggle with chronic, pervasive depressive and residual manic symptoms. The authors provide everything needed to conduct the 12 weekly group sessions, which are supplemented by regular individual sessions. Reproducible tools include 29 client handouts and an Instructor Checklist. Purchasers get access to a companion website featuring downloadable audio recordings of the guided mindfulness practices (meditations and mindful movement), plus the reproducible materials, ready to download and print in a convenient 8 1/2 x 11 size. A separate website for use by clients features the audio recordings only.