Exploring Mathematical Modeling in Biology through Case Studies and Experimental Activities provides supporting materials for courses taken by students majoring in mathematics, computer science or in the life sciences. The book's cases and lab exercises focus on hypothesis testing and model development in the context of real data. The supporting mathematical, coding and biological background permit readers to explore a problem, understand assumptions, and the meaning of their results. The experiential components provide hands-on learning both in the lab and on the computer. As a beginning text in modeling, readers will learn to value the approach and apply competencies in other settings. Included case studies focus on building a model to solve a particular biological problem from concept and translation into a mathematical form, to validating the parameters, testing the quality of the model and finally interpreting the outcome in biological terms. The book also shows how particular mathematical approaches are adapted to a variety of problems at multiple biological scales. Finally, the labs bring the biological problems and the practical issues of collecting data to actually test the model and/or adapting the mathematics to the data that can be collected.

A fresh consideration of the enduring tradition of the Seven Deadly Sins, showing its continuing post-medieval influence. The tradition of the seven deadly sins played a considerable role in western culture, even after the supposed turning-point of the Protestant Reformation, as the essays collected here demonstrate. The first part of the book addresses such topics as the problem of acedia in Carolingian monasticism; the development of medieval thought on arrogance; the blending of tradition and innovation in Aquinas's conceptualization of the sins; the treatment of sin in the pastoral contexts of the early Middle English Vices and Virtues and a fifteenth-century sermon from England; the political uses of the deadly sins in the court sermons of Jean Gerson; and the continuing usefulnessof the tradition in early modern England. In the second part, the role of the tradition in literature and the arts is considered. Essays look at representations of the sins in French music of the thirteenth to the fifteenth centuries; in Dante's Purgatorio; in a work by Michel Beheim in pre-Reformation Germany; and in a 1533 play by the German Lutheran writer Hans Sachs. New interpretations are offered of Gower's "Tale of Constance" and Bosch's Tabletop of the Seven Deadly Sins. As a whole, the book significantly enhances our understanding of the multiple uses and meanings of the sins tradition, not only in medieval culture but also in the transition from the medievalto the early modern period. RICHARD G. NEWHAUSER is Professor of English and Medieval Studies, Arizona State University, Tempe; SUSAN J. RIDYARD is Professor of History and Director of the Sewanee Medieval Colloquium,The University of the South, Sewanee. Contributors: Richard G. Newhauser, James B. Williams, Kiril Petkov, Cate Gunn, Eileen C. Sweeney, Holly Johnson, Nancy McLoughlin, Anne Walters Robertson, Peter S. Hawkins, CarolJamison, Henry Luttikhuizen, William C. McDonald, Kathleen Crowther.

The Ugly Duckling looks different. He doesn't fit in with the other birds ... until he changes one day. An accessible introduction to modern languages, these billingual readers introduce the best loved fairy tales with parallel text in English and French.

Guillaume de Machaut, renowned fourteenth-century French composer and poet, wrote the first polyphonic Mass and many other important musical works. Friend of royalty, prelates, noted poets and musicians, Machaut was a cosmopolitan presence in late medieval Europe. He also served as canon of the cathedral of Reims, an ancient and influential archiepiscopal see and the coronation site of French kings. This exploration of Machaut's life and work focuses on his music based on ecclesiastical chants: twenty-three motets, the David Hocket, and the Mass of Our Lady. The meaning of his music can often be understood through study of its context in fourteenth-century Reims. Machaut emerges as a composer deeply involved in the great crises of his day, one who skilfully and artfully expresses profound themes of human existence in ardent music and poetry.

The Royal Abbey of Saint-Denis was founded in honour of Dionysius, one of seven missionaries sent from Rome to Gaul around 250. It grew to be one of the most powerful monasteries in western Christendom and enjoyed a central position in French history as the first Gothic abbey, royal necropolis, and place of origin of the chronicles of the kings. This is a study of the music and ritual at Saint-Denis from the sixth to the sixteenth century. It is based on an examination of the liturgical books and archival sources relating to the abbey, in particular the surviving service-books, which tell us much about the history of the music and of the Divine Office at Saint-Denis. Anne Robertson also looks at the tropes and sequences proper to the office for Saint-Denis, provides information on the performance practices, instruments, musicians, and liturgists from the abbey, and offers an account of the history of the liturgy from the Council of Tours in 567 to the pillage of the abbey by the Huguenots in 1567, thus explicating the extant liturgical codices from Saint-Denis. For the author the ritual and history of the abbey is also inextricably linked to the reconstruction of its various buildings, the decorations of the church, even the monks' ambitions. This is a fascinating and wide-ranging study of this extraordinary institution.

This is a beautiful billingual English-Polish edition of Sleeping Beauty. An accessible introduction to modern languages, these billingual readers Introduce the best loved fairy tales with parallel text in English and Polish. Stories are told in approximately 400 words and are supported by modern artwork. The two languages are in a different fonts to help distinguish them clearly on each spread. As well as a perfect approach to learning a new language for the first time, these books will be a useful tool for EAL teaching as well. The texts are perfectly pitched for chidlren aged 5-7 and up.

A collection of five present-day Sherlock Holmes stories that poke gentle fun at the idiosyncrasies of modern life - not to mention the eccentric detective and his world-weary friend who are at the heart of the action. Stuck in a dysfunctional marriage and the job from hell, aspiring writer Doctor John H Watson battles against the angst of a midlife crisis whilst being drawn further into the individual world of his friend - the irascible, difficult but brilliant consulting detective, Sherlock Holmes. Each story is based directly on an adventure from the original work of Sir Arthur Conan Doyle, but updated with a modern-day twist. Instead of the foggy cobbled streets and hansom cabs of Victorian London, we get over-paid footballers, pop-stars, a glamour model, the tabloid press and social media. But friendship and Holmes' unique science of deduction remain central to each story.

To celebrate the release of her novel Barefoot on Baker Street, Charlotte Anne Walters undertook the task of reading and reviewing one of the original Sherlock Holmes short stories every day until she had completed all 56. The reviews were posted daily on her blog and attracted viewers from all over the world. The reviews are full of humour and Holmesian insight, ending in a score out of ten for each story. This book contains all 56 blogs plus additional material including reviews of Sir Arthur Conan Doyle's four Holmes novels. Although it was a pleasure for a life-long Holmes admirer to re-visit the stories, trying to do this on top of holding down a busy full-time job and family commitments was a big challenge - resulting in some stressful but comical moments detailed in the blogs. Even Mr Walters couldn't resist throwing in a few comments of his own. Charlotte is donating all her royalties from this publication to the Undershaw Preservation Trust, a charity striving to protect and restore the former home of Sir Arthur Conan Doyle - saveundershaw.com.

Fully revised and updated 2nd edition. Barefoot on Baker Street is set in late Victorian London where a life of crime is the only way to escape poverty and servitude for one bright young workhouse orphan. The narrative follows Red on her incredible life-journey as it twists and turns through poverty, riches, infatuation, loss and love. A dramatic escape from the workhouse at thirteen propels Red into a world of slum housing, street gangs, prostitution and petty crime as the rapidly expanding city groans under the weight of the industrial revolution. A chance meeting with the mysterious and eccentric Sherlock Holmes prompts an infatuation which cuts through her street-wise bravado. Red's blossoming criminal career also brings her to the attention of Professor James Moriarty. An autistic savant riddled with obsessive compulsions, Moriarty is a dangerous criminal who draws Red into his life and onto a collision course with Holmes.

Barefoot on Baker Street is set in late Victorian London where a life of crime is the only way to escape poverty and servitude for one bright young workhouse orphan. The narrative follows Red on her incredible life-journey as it twists and turns through poverty, riches, infatuation, loss and love. A dramatic escape from the workhouse at thirteen propels Red into a world of slum housing, street gangs, prostitution and petty crime as the rapidly expanding city groans under the weight of the industrial revolution. A chance meeting with the mysterious and eccentric Sherlock Holmes prompts an infatuation which cuts through her street-wise bravado. Red's blossoming criminal career also brings her to the attention of Professor James Moriarty. An autistic savant riddled with obsessive compulsions, Moriarty is a dangerous criminal who draws Red into his life and onto a collision course with Holmes.

This scarce antiquarian book is a selection from Kessinger Publishing's Legacy Reprint Series. Due to its age, it may contain imperfections such as marks, notations, marginalia and flawed pages. Because we believe this work is culturally important, we have made it available as part of our commitment to protecting, preserving, and promoting the world's literature. Kessinger Publishing is the place to find hundreds of thousands of rare and hard-to-find books with something of interest for everyone!