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As far as we are aware, this is the first attempt to cover the com
parative physiology of the pancreatic islets in a monograph. The
topics discussed would probably have sufficed to fill about half a
dozen monographs, a matter that becomes obvious from a look at the
Contents. Hence, we have tried to present the ma terial more in the
form of a digest, to emphasize evolutionary perspectives, to point
out critical issues, and to identify challenging topics for future
research. This approach required an arbitrary reduction of the num
ber of references, and we therefore join the chorus of recent
authors who beg their colleagues for understanding if some of their
publications do not appear in the bibliography. Keeping up with the
current literature was like fighting one of those monsters that
grow a couple of new heads for each one that is cut off.
Nevertheless, we hope that we have covered most of the key
publications up to the autumn of 1986. We gratefully acknowledge
the advice of many colleagues, and in particular the invaluable
criticisms of Robert L. Hazelwood and Erika Plisetskaya. Special
thanks are due to the series editor, Donald S. Farner, for his
patience and guidance, both of which were fresh proof of his
legendary diplomatic skills. Finally, we wish to thank Dr. D.
Czeschlik and his staff at the Springer Verlag for their patience
and support. Philadelphia, PA AUGUST EpPLE Greenville, NC JACK E.
BRINN September 1987 v Contents Chapter 1. Introduction
.......................... ."
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