Business as usual’ is not a sustainable strategy in the 21st-century workplace. Organisations have to adapt in order to thrive in the contexts of a transforming South Africa and increasing exposure to the global economy.

South African and African organisations need interventions based on international knowledge and best practices but supplemented with African research and application. In Fundamentals of Organisation Development and Change Management, the authors have combined their extensive local and international experience in the practice of organisation development and change management to present the student, manager and science practitioner with the fundamentals they need to facilitate change initiatives.

Key Features/ Benefits:

• Approaches to organisation development and change management
• The differences between organisation development and change management classic organisation development models and theories, combined with latest developments in the field
• A practical, structured approach to change managementcase studies in the South African context enriched learning activities throughout the text with added reflective questions, multiple choice questions and case studies at the end of each chapter.

The book covers the core concepts of organisation development with a good balance between theory and application, and is accessible to the novice student, manager and science practitioner of OD. Although the practice of organisation development is growing rapidly in South Africa and neighbouring countries, the lack of academic books on the subject for undergraduate students to serve as a foundation in this field poses a challenge. The aim of this book is to address this gap.

Volume 42 of "Progress in Drug Research" contains seven reviews and the various indexes which facilitate its use and establish the con nection with the previous volumes. The articles in this volume deal with organization and management of drug research; luteinizing hor mone regulators; natural products as anticancer agents; flavonoids and their pharmacological activity; serenics in the control of mental disturbances; Transfer Factor and its application and with Transfer Factor in malignancy. In the 34 years that "Progress in Drug Research" has existed, the Edi tor has enjoyed the valuable help and advice of many colleagues. Readers, the authors of the reviews, and last but not least, the review ers have all contributed greatly to the success of this series. Although the comments received so far have generally been favorable, it is nevertheless necessary to analyze and to reassess the current position and the future direction of such a review series. So far, it has been the Editors intention to help disseminate informa tion on the vast domain of drug research, and to provide the reader with a tool with which to keep abreast of the latest developments and trends. The reviews in PDR are useful to the non-specialists, who can obtain an overview of a particular field of drug research in a rela tively short time."

S. Ren and E.J. Lien: CaCo-2 cell permeability vs human gastrointestinal absorption: QSPR analysis.- J.C.G. Halford and J.E. Blundell: Pharmacology of appetite suppression.- B. Olivier, W. Soudijn and I. van Wijngaarden: Serotonin, dopamine and norepinephrine transporters in the central nervous system and their inhibitors.- D. Poyner, H. Cox, M. Bushfield, J.M. Treherne and M.K. Demetrikopoulos: Neuropeptides in drug research.- M. Kumari and M.K. Ticku: Regulation of NMDA receptors by ethanol.- H. Horikoshi, T. Hashimoto and T. Fujiwara: Troglitazone and emerging glitazones: new avenues for potential therapeutic benefits beyond glycemic control.- Rosamund C. Smith and Simon J. Rhodes: Applications of developmental biology to medicine and animal agriculture

. Aggression research is in a rapid state of development. The accelerating knowledge of neurotransmitter systems in the brain, their behavioural functions and the development of drugs which may specifically affect systems related to attack and defence is fruitfully combined with studies in which basic ethological observation and quantification techniques are used more routinely. Moreover, much of the experimental effort has finally applied some order to the initial chaos which afflicted the various experimental aggression models used in pharmacological, physiological and ethological research. This highly desirable trend not only leads to a better understanding of the phenomena studied and the terminologies employed, but it increases our awareness of the multiplicity of factors that are important, making it difficult to allow over hasty and simple generalizations. This book is a compilation of studies presented at the International Society for Research on Aggression meeting in Chicago 1986, in which leading investigators were invited to cover aspects of ethopharmacological aggression research in a wide variety of species, including studies on humans. The level to which ethological techniques have been incorporated into the various areas of research differs, as well as the knowledge and understanding of the neurotransmitter and experimental drug action on brain functioning in mammalian species. This naturally results in data which are not always easy to compare or to extrapolate between species but useful indicators are starting to emerge.

Olivier Dorget nous permet d'ameliorer notre comprehension des relations hommes-femmes en nous donnant les cles du succes utilisees spontanement par certains couples. Dans un style clair et leger, l'homme est divulgue a la femme et la femme est revelee a l'homme. Duo permet a tout un chacun de redecouvrir de belles emotions en esquivant la routine, veritable ennemie d'une vie amoureuse et sentimentale epanouie. Ce livre peut changer positivement le regard que l'on porte sur son partenaire. Le sujet y est traite de maniere inedite et agreable. Vous y trouverez des exemples, des concepts precieux et des actions concretes a appliquer immediatement puis dans le temps. Isa B. OlivierDorget.fr