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This book covers wide areas of animal and human psychopharmacology
with clinical utility in the treatment of psychiatric and
neurological (e.g Alzheimer's disease) disorders. The main theme is
to develop a new paradigm for drug discovery that questions the
claim that animal models or assays fail adequately to predict Phase
3 clinical trials. A new paradigm is advocated that stresses the
importance of intermediate staging points between these extremes
that depend on suitable translation of findings from animal studies
to Phase 1 or Phase 2 studies utilising experimental medicine.
This book covers wide areas of animal and human psychopharmacology
with clinical utility in the treatment of psychiatric and
neurological (e.g Alzheimer's disease) disorders. The main theme is
to develop a new paradigm for drug discovery that questions the
claim that animal models or assays fail adequately to predict Phase
3 clinical trials. A new paradigm is advocated that stresses the
importance of intermediate staging points between these extremes
that depend on suitable translation of findings from animal studies
to Phase 1 or Phase 2 studies utilising experimental medicine.
Cognitive neuroscience isĀ theĀ interdisciplinary study
of how cognitive and intellectual functions are processed and
represented within the brain, which is critical to building
understanding of core psychological and behavioural processes such
as learning, memory, behaviour, perception, and consciousness.
Understanding these processes not only offers relevant fundamental
insights into brain-behavioural relations, but may also lead to
actionable knowledge that can be applied in the clinical treatment
of patients with various brain-related disabilities. This Handbook
examines complex cognitive systems through the lens of
neuroscience, as well as providing an overview of development and
applications within cognitive and systems neuroscience research and
beyond. Containing 35 original, state of the art contributions from
leading experts in the field, this Handbook is essential reading
for researchers and students of cognitive psychology, as well as
scholars across the fields of neuroscientific, behavioural and
health sciences. Part 1: Attention, Learning and Memory Part 2:
Language and Communication Part 3: Emotion and Motivation Part 4:
Social Cognition Part 5: Cognitive Control and Decision Making Part
6: Intelligence
Cognitive neuroscience isĀ theĀ interdisciplinary study
of how cognitive and intellectual functions are processed and
represented within the brain, which is critical to building
understanding of core psychological and behavioural processes such
as learning, memory, behaviour, perception, and consciousness.
Understanding these processes not only offers relevant fundamental
insights into brain-behavioural relations, but may also lead to
actionable knowledge that can be applied in the clinical treatment
of patients with various brain-related disabilities. This Handbook
focusses on the foundational principles, methods, and underlying
systems in cognitive and systems neuroscience, as well as examining
cutting-edge methodological advances and innovations. Containing 34
original, state of the art contributions from leading experts in
the field, this Handbook is essential reading for researchers and
students of cognitive psychology, as well as scholars across the
fields of neuroscientific, behavioural and health sciences. Part 1:
Background Considerations Part 2: Neuroscientific Substrates and
Principles Part 3: Neuroanatomical Brain Systems Part 4: Neural
Dynamics and Processes Part 5: Sensory-Perceptual Systems and
Cognition Part 6: Methodological Advances
Clinical Neuropsychology is a vast and varied field that focuses on
the treatment, assessment and diagnosis of a range of cognitive
disorders through a study and understanding of neuroanatomy and the
relationship between the brain and human behavior. This handbook
focuses on specific Neuropsychological disorders. It covers each of
the classification systems involved before moving on to specific
types of disorders from neurodevelopmental to neuropathological as
well as brain injuries, trauma and neurodegenerative disorders.
This handbook not only provides an in-depth overview of these
Neuropsychological disorders, but also explores the history of the
field as well its global challenges. The handbook is an essential
tool for clinicians and scientists, as well as postgraduate
students and researchers in a range of disciplines exploring the
area. PART I BACKGROUND CONSIDERATIONS PART II NEURODEVELOPMENTAL
DISORDERS PART III NEUROLOGICAL DISORDERS PART IV NEUROCOGNITIVE
DISORDERS PART V TRAUMATIC BRAIN INJURY PART VI PSYCHIATRIC
DISORDERS
Clinical Neuropsychology is a vast and varied field that focuses on
the treatment, assessment and diagnosis of a range of cognitive
disorders through a study and understanding of neuroanatomy and the
relationship between the brain and human behavior. This handbook
focuses on the assessment, diagnosis and rehabilitation of
cognitive disorders. It provides in-depth coverage on a variety of
content, including psychometrics, neuropsychological test batteries
(computer based cognitive assessment systems) and assessment
applications. This handbook is vital for clinical
neuropsychologists and postgraduate students and researchers hoping
to apply a knowledge of neuropsychology to clinical settings and
effectively assess, diagnose and treat patients suffering from
cognitive disorders. PART I BACKGROUND CONSIDERATIONS PART II
DOMAIN-SPECIFIC NEUROPSYCHOLOGICAL MEASURES PART III GENERAL
COGNITIVE TEST BATTERIES PART IV LEGACY NEUROPSYCHOLOGICAL TEST
BATTERIES PART V COMPUTERISED BATTERIES, TECHNOLOGICAL ADVANCES AND
TELENEUROPSYCHOLOGY PART VI NEUROPSYCHOLOGICAL ASSESSMENT
APPLICATIONS
The recent explosion of neuroscience techniques has proved to be
game changing in terms of understanding the healthy brain, and in
the development of neuropsychiatric treatments. One of the key
techniques available to us is functional magnetic resonance imaging
(fMRI), which allows us to examine the human brain non-invasively,
and observe brain activity in real time. Through fMRI, we are
beginning to build a deeper understanding of our thoughts,
motivations, and behaviours. Recent reports that some patients who
have all indications of being in a persistent vegetative state
actually show conscious awareness, and were able to communicate
with researchers, demonstrate perhaps the most remarkable and
dramatic use of fMRI. But this is just the most striking of a
number of areas in which fMRI is being used to 'read minds', albeit
in a very limited way. As neuroscientists unravel the regions of
the brain involved in reward and motivation, and in romantic love,
we are likely to develop the capacity to influence responses such
as love using drugs. fMRI studies have also been used to indicate
that many people who would not regard themselves as racist show a
racial bias in their emotional responses to faces of another racial
group. Meanwhile, the reliability of fMRI as a lie detector in
murder cases is being debated - what if the individual simply
believes, falsely, that he or she committed a murder? Sex, Lies,
and Brain Scans takes readers beyond the media headlines. Barbara
J. Sahakian and Julia Gottwald consider what the technique of fMRI
entails, and what information it can give us, showing which
applications are possible today, and which ones are science
fiction. They also consider the important ethical questions these
techniques raise. Should individuals applying for jobs as teachers
or judges be screened for unconscious racial bias? What if the
manipulation of love using 'love potions' was misused for economic
or military ends? How far will we allow neuroscience to go? It is
time to make up our minds.
The recent explosion of neuroscience techniques has been
game-changing in terms of understanding the healthy brain, and in
the development of neuropsychiatric treatments. One of the key
techniques is functional magnetic resonance imaging (fMRI), which
allows us to examine the human brain non-invasively, and observe
brain activity in real time. Through fMRI, we are beginning to
build a deeper understanding of our thoughts, motivations, and
behaviours. Already fMRI has been used to detect conscious activity
in some patients who had all indications of being in a vegetative
state, and even enabled us to communicate with some of them. This
is just one of the many striking areas in which fMRI can be used to
'read minds'. As neuroscientists unravel the brain networks of
self-control and morality, we might find abnormalities in criminal
offenders. Could we predict crimes before they are committed? fMRI
has also been used to detect racial bias in some people who
regarded themselves as fair-minded. Meanwhile, the reliability of
fMRI as a lie detector in murder cases or as a tool for marketing
is being debated. Sex, Lies, and Brain Scans takes readers beyond
the media headlines. Barbara Sahakian and Julia Gottwald consider
what the technique of fMRI entails, and what information it can
give us, showing which applications are possible today, and which
ones are science fiction. They also consider the important ethical
questions these techniques raise. Should brain scans be allowed at
airports to screen for terrorists? Should they be used to vet
future judges and teachers? How far will we allow neuroscience to
go? It is time to make up our minds.
Cognitive neuroscience isĀ theĀ interdisciplinary study
of how cognitive and intellectual functions are processed and
represented within the brain, which is critical to building
understanding of core psychological and behavioural processes such
as learning, memory, behaviour, perception, and consciousness.
Understanding these processes not only offers relevant fundamental
insights into brain-behavioural relations, but may also lead to
actionable knowledge that can be applied in the clinical treatment
of patients with various brain-related disabilities. The first
volume of this two-volume set focusses on the foundational
principles, methods, and underlying systems in cognitive and
systems neuroscience, as well as exploring cutting-edge
methodological advances and innovations. The second volume examines
complex cognitive systems through the lens of neuroscience, as well
as providing an overview of development and applications within
research and real-world contexts. Containing 69 original, state of
the art contributions from leading experts in the field, this
Handbook is essential reading for researchers and students of
cognitive psychology, as well as scholars across the fields of
neuroscientific, behavioural and health sciences. Volume 1:
Neuroscientific Principles, Systems and Methods Part 1: Background
Considerations Part 2: Neuroscientific Substrates and Principles
Part 3: Neuroanatomical Brain Systems Part 4: Neural Dynamics and
Processes Part 5: Sensory-Perceptual Systems and Cognition Part 6:
Methodological Advances Volume 2: Cognitive Systems, Development
and Applications Part 1: Attention, Learning and Memory Part 2:
Language and Communication Part 3: Emotion and Motivation Part 4:
Social Cognition Part 5: Cognitive Control and Decision Making Part
6: Intelligence
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