IN "THE ANTIDOTE," Barry Werth draws upon unprecedented inside reporting spanning more than two decades to provide a groundbreaking closeup of the upstart pharmaceutical company Vertex and the ferocious but indispensable world of Big Pharma that it inhabits.
In 1989, the charismatic Joshua Boger left Merck, then America's most admired business, to found a drug company that would challenge industry giants and transform health care. Werth described the company's tumultuous early days during the AIDS crisis in "The Billion-Dollar Molecule," a celebrated classic of science and business journalism. Now he returns to tell a riveting story of Vertex's bold endurance and eventual success.
The $325 billion-a-year pharmaceutical business is America's toughest and one of its most profitable. It's riskier and more rigorous at just about every stage than any other business, from the towering biological uncertainties inherent in its mission to treat disease; to the 30-to-1 failure rate in bringing out a successful medicine even after a molecule clears all the hurdles to get to human testing; to the multibillion-dollar cost of ramping up a successful product; to operating in the world's most regulated industry, matched only by nuclear power.
Werth captures the full scope of Vertex's twentyfive- year drive to deliver breakthrough medicines. At a time when America struggles to maintain its innovative edge, "The Antidote" is a powerful inside look at one of the most intriguing and important business stories of recent decades.

Join journalist Barry Werth as he pulls back the curtain on Vertex, a start-up pharmaceutical company, and witness firsthand the intense drama being played out in the pioneering and hugely profitable field of drug research. Founded by Joshua Boger, a dynamic Harvard- and Merck-trained scientific whiz kid, Vertex is dedicated to designing -- atom by atom -- both a new life-saving immunosuppressant drug, and a drug to combat the virus that causes AIDS.

You will be hooked from start to finish, as you go from the labs, where obsessive, fiercely competitive scientists struggle for a breakthrough, to Wall Street, where the wheeling and dealing takes on a life of its own, as Boger courts investors and finally decides to take Vertex public. Here is a fascinating no-holds-barred account of the business of science, which includes an updated epilogue about the most recent developments in the quest for a drug to cure AIDS.

DAMAGES is the riveting true story of one family's legal struggles in the world of medicine. At the urging of a friend, the Sabias filed a medical malpractice lawsuit against Dr. Humes and Norwalk Hospital. Barry Werth takes us through the seven-year lawsuit, allowing us to see the legal strategy plotted by the Sabias' attorneys, Connecticut's premier medical malpractice law firm.

In "Banquet at Delmonico's," Barry Werth draws readers inside the circle of intellectuals, scientists, politicians, businessmen, and clergymen who brought Charles Darwin's controversial ideas to post-Civil-War America. Each chapter is dedicated to a crucial intellectual encounter, culminating with an exclusive farewell dinner held in English philosopher Herbert Spencer's honor at the venerable New York restaurant Delmonico's in 1882. In this thought-provoking and nuanced account, Werth firmly situates social Darwinism in the context of the Gilded Age. "Banquet at Delmonico's "is social history at its finest.

In "31 Days," acclaimed historian Barry Werth takes readers inside the White House during the tumultuous days of August 1974, following Richard Nixon's resignation and the swearing-in of America's "accidental president," Gerald Ford.
The Watergate scandal had torn the country apart. In a dramatic, day-by-day account of the new administration's inner workings, Werth shows how Ford, caught between political expedience, the country's demands for justice, and his own moral compass, struggled valiantly to restore the nation's tarnished faith in its leadership. With deft and refreshing analysis Werth illuminates how this unprecedented political upheaval produced new fissures and battle lines, as well as new opportunities for political advancement for ambitious young men such as Donald Rumsfeld, who had been Nixon's ambassador to NATO, and Dick Cheney, already coolly efficient as Rumsfeld's former deputy. A superbly crafted presidential history with all of the twists and turns of a thriller, "31 Days" sheds new light on the key players and political dilemmas that reverberate in today's headlines.