Techniques for Downstream process for Biologic Drugs and Vaccines provides comprehensive technologies involved in processing postharvest broth to separate the target biological therapeutic products of extracellular or intercellular aspects in nature - to its highest purification form, and to thus make it acceptable to end users. The technologies involved in the post-harvesting of fermented broth are explained in this comprehensive resource in a simplified manner with different case studies to help non-engineering students and scientists easily capture the basic principle of biomass processing technologies and their applications in new projects related to the development and manufacturing of therapeutic bio-products. As conceptual development of biotechnology has taken new shape and style with the integration of medical sciences, physical science, and engineering, and has thus begun the need for the development of microbial or cell line process technology and application for large-scale isolation and purification of metabolites or vaccines through the fermentation process, this book covers the most important aspects.

This book presents a concept for implementing a mass balance approach toward developing an effective eco-friendly, livestock farming system independent of external energy input. In this context it describes a modern, integrated farming system, and includes comprehensive technical information explaining the design and evaluation of manure management systems, and modeling and operational tools. It first discusses the mass balance operating process, highlighting the difference between imported and exported mass across the farm boundary. Estimating mass balance can provide critical information for (comprehensive) nutrient management planning and for managing the movement of nutrients and manure. It then explains the estimation of whole-farm P mass balance using a suitable model system. The subsequent chapters provide updated information on management aspects of livestock-farming and generation of multiple job opportunities, and also explore various aspects of livestock farming operational protocols like housing and management; nurture of rams, ewes and lambs, new born calves and heifers; care of buck, doe and kid- nutrition flushing; concept zero grazing-systems; disease control and management; integrated goat farming; and crop-livestock integration. Further, the book addresses crop-livestock integration; energy autonomy in cattle farming; value added biopharmaceuticals from cattle farming; CAPEX for cattle farming; concepts of cattle farming; detrimental effects of the industry; topographic and edaphic factors, and thermal stress on livestock growth and development; socioeconomic development; and water requirements for livestock. The book concludes with the most important issue in the field of agriculture and veterinary science: "Livestock Farming with Care," describing sustainable, eco-friendly livestock farming by highlighting issues like animal feed vs. human food; agricultural GDP vs livestock, and factors affecting the sustainability of livestock farming. Given its scope, this book is a valuable resource for researchers and students alike, and will also appeal to practitioners in the field of livestock.

Tailoring of biomolecules using protein engineering technology, and host cells culture techniques are among the most sophisticated and elegant achievements of modern applied life sciences in which the basic fundamentals biotechnology are applicable for the development and manufacturing of biologics and other related bio-molecules for a hurdle free life with good health. A majority of biologics derived from genetically modified host cells in the current market are bio-formulation such as antibodies, nucleic acid products and vaccines. Such bio-formulations are developed mainly in two steps i.e. upstream process and downstream process. The first volume of this series begins with the latest information on how the classical stepwise host cells culture (mammals, animals, plants, and bacteria) methodology has been changed to fully continuous or partially continuous host cells culture process in order to economise the biopharmaceutical products manufacturing process. In addition this volume narrates a brief history on conceptual development of new thoughts in designing biotechnology industries for commercial production of variety of therapeutic proteins with structural modification on the basis of clinical requirements. The readers will feel exited by going through the latest discovery and development in applied life sciences for designing innovative biomolecules for health care with utmost safe. The most interesting part of this volume is newly developed concept on bioprinting. It explains how to design and fabricate animate objects by fusing or depositing material of interest in the form of powders, solid dusts, metal, liquid or even living cells or tissues by layers to produce 3D objectives. The first volume ends with the latest information on the current trend in biologics market, market dynamic, drives, and opportunities with challenges.

This book presents a concept for implementing a mass balance approach toward developing an effective eco-friendly, livestock farming system independent of external energy input. In this context it describes a modern, integrated farming system, and includes comprehensive technical information explaining the design and evaluation of manure management systems, and modeling and operational tools. It first discusses the mass balance operating process, highlighting the difference between imported and exported mass across the farm boundary. Estimating mass balance can provide critical information for (comprehensive) nutrient management planning and for managing the movement of nutrients and manure. It then explains the estimation of whole-farm P mass balance using a suitable model system. The subsequent chapters provide updated information on management aspects of livestock-farming and generation of multiple job opportunities, and also explore various aspects of livestock farming operational protocols like housing and management; nurture of rams, ewes and lambs, new born calves and heifers; care of buck, doe and kid- nutrition flushing; concept zero grazing-systems; disease control and management; integrated goat farming; and crop-livestock integration. Further, the book addresses crop-livestock integration; energy autonomy in cattle farming; value added biopharmaceuticals from cattle farming; CAPEX for cattle farming; concepts of cattle farming; detrimental effects of the industry; topographic and edaphic factors, and thermal stress on livestock growth and development; socioeconomic development; and water requirements for livestock. The book concludes with the most important issue in the field of agriculture and veterinary science: "Livestock Farming with Care," describing sustainable, eco-friendly livestock farming by highlighting issues like animal feed vs. human food; agricultural GDP vs livestock, and factors affecting the sustainability of livestock farming. Given its scope, this book is a valuable resource for researchers and students alike, and will also appeal to practitioners in the field of livestock.

This book sheds new light on how microbes can be used as effective and sustainable resources to produce green energy in the form of biogas, algal diesel, ethanol, hydrogen and direct electricity. It discusses topics such as microbial energy conversion technologies, including ethanol production by microbial catalytic reaction, biomethanization, biodiesel from microalgae, microbial fuel cells, and the microbiological production of hydrogen. The book will inspire scientists to find new approaches to meet local energy demands with the help of sustainable microbial resources available in and around a given location.

This book describes how microbes can be used as effective and sustainable resources to meet the current challenge of finding suitable and economical solutions for biopharmaceuticals, enzymes, food additives, nutraceuticals, value added biochemicals and microbial fuels, and discusses various aspects of microbial regulatory activity and its applications. It particularly focuses on the design, layout and other relevant issues in industrial microbe applications. Moreover, it discusses the entire microbial-product supply chain, from manufacturing sites to end users, both in domestic and international markets, providing insights into the global marketing of microbes and microbial biomass-derived products. Further, it includes topics concerning the effective production and utilization of eco-friendly biotechnology industries. It offers a valuable, ready-to-use guide for technologists and policymakers developing new biotechnologies.

This book describes how microbes can be used as effective and sustainable resources to meet the current challenge of finding suitable and economical solutions for biopharmaceuticals, enzymes, food additives, nutraceuticals, value added biochemicals and microbial fuels, and discusses various aspects of microbial regulatory activity and its applications. It particularly focuses on the design, layout and other relevant issues in industrial microbe applications. Moreover, it discusses the entire microbial-product supply chain, from manufacturing sites to end users, both in domestic and international markets, providing insights into the global marketing of microbes and microbial biomass-derived products. Further, it includes topics concerning the effective production and utilization of eco-friendly biotechnology industries. It offers a valuable, ready-to-use guide for technologists and policymakers developing new biotechnologies.

This book sheds new light on how microbes can be used as effective and sustainable resources to produce green energy in the form of biogas, algal diesel, ethanol, hydrogen and direct electricity. It discusses topics such as microbial energy conversion technologies, including ethanol production by microbial catalytic reaction, biomethanization, biodiesel from microalgae, microbial fuel cells, and the microbiological production of hydrogen. The book will inspire scientists to find new approaches to meet local energy demands with the help of sustainable microbial resources available in and around a given location.

Healthcare Strategies and Planning for Social Inclusion and Development: Volume One: Health for All - Challenges and Opportunities in Healthcare Management examines health care management, particularly in developing countries, along with the key aspects of universal health required to address current global health issues. This new volume begins with an overview of the concept and definition of "Health for All." The book covers how international organizations like the WHO support national health authorities in managing their core healthcare systems, support healthcare workforces, utilize technologies like health information systems, ensure health coverage and funding, and provide primary healthcare education. This volume is a useful resource to graduate students in public health and health care policy, public health professionals, health and social work researchers, and health policy makers interested in global health and primary healthcare services, particularly in developing countries.

Healthcare Strategies and Planning for Social Inclusion and Development: Volume Two: Social, Economic, and Health Disparities of Rural Women examines rural women, particularly in developing countries, and how social and economic constraints they experience impact their ability to advocate for their own health and impede their access to healthcare. This volume discusses the economic and social barriers rural women confront in exercising their right to health care. It explains how geographical isolation, economic instability, healthcare provider shortages, lack of appropriate funding, resource limitations, and lack of health education are just few factors that make rural health care difficult. The book also covers the impact of social isolation on the health needs of rural women which include chronic diseases, mental health, and OB/GYN services as well as how the lack of opportunities for formal education restrict rural women from working outside the household. This volume will be a useful resource to graduate students in public and global health, public health professionals, health and social work researchers, and health policymakers interested in women's health, especially in developing countries.

This book is a practical manual for goat production systems covering: breeding and selection, feeding based on available crops and resources, and targeted preventative health care for increased productivity and income. It outlines best practice and strategies for setting up a farm, overcoming challenges, increasing milk and meat quality, obtaining sustainability, reducing environmental pollution, optimising climatic conditions and tapping into local know-how. In addition, the book details developing region-specific data for effective decision making and better management, as well as how to run a developmental project to empower stake holders for higher production, support innovation, and analyse the supply chain for better product quality and marketing.

Conceptual Development of Industrial Biotechnology for Commercial Production of Biopharmaceuticals and Vaccines provides insights on how to bring sustainability into biologic drug production. The cumulative facts and figures within in the book are helpful to promoters in monitoring value chain transfer process of super quality biologics for better return in profits. In addition, this is a useful reference for students, researchers and scientists in biotechnology, pharmaceutical science, medical sciences, and the R&D division of biotechnology-based industries. Conceptual development of biotechnology has taken new avenues with the integration of medical sciences, physical science, and engineering, hence this is a timely source. The current global market for vaccines, especially COVID-19, is tremendous. Bivalent oral polio vaccine, diphtheria, tetanus-containing, and measles-containing vaccines have a high demand internationally and recombinant DNA technology and protein engineering are helpful in the production of quality bio-products.

Environmental Technology and Sustainability: Physical, Chemical and Biological Technologies for Clean Environmental Management provides a dependable source of information on the fundamental scientific evidence involved in environmental protection and sustainable development. The book provides the basic natural sciences that underpin the understanding, development and application of environment technologies that support a clean inhabitable world that includes environmental technologies and sustainable, renewable energy systems. It considers the science and technology for environmental benefits, including the development of both smarter, cleaner technologies for environmental protection, conservation, and more.