0
Your cart

Your cart is empty

Browse All Departments
  • All Departments
Price
  • R2,500 - R5,000 (2)
  • -
Status
Brand

Showing 1 - 2 of 2 matches in All Departments

Graves' Disease - Pathogenesis and Treatment (Hardcover, 2000 ed.): Basil Rapoport, Sandra M. McLachlan Graves' Disease - Pathogenesis and Treatment (Hardcover, 2000 ed.)
Basil Rapoport, Sandra M. McLachlan
R4,532 Discovery Miles 45 320 Ships in 10 - 15 working days

From the perspective of the investigator, Graves' disease is a fascinating disorder with unique features and opportunities for study. The discovery in 1956 that Graves' disease was caused by a humoral factor, later shown to be an antibody to the TSH receptor, was a triumph for modern investigative medicine. Rapid progress is now being made in (i) understanding the molecular interaction between autoantibodies and the TSH receptor, (ii) identifying the genes that contribute to the predisposition to disease, (iii) developing an animal model of Graves' disease, and (iv) identifying the long-sought orbital antigen in ophthalmopathy. From the clinical standpoint, although Graves' disease is eminently treatable, there is no definitive cure. None of the therapeutic options are ideal. It is hoped that rapid progress in understanding the pathogenesis of the disease will lead to the ultimate goal of some form of immunotherapy that will make antithyroid drugs, radioiodine and thyroidectomy obsolete. The chapters in Graves' Disease: Pathogenesis and Treatment represent the viewpoints of many prominent clinicians and investigators working in the field. The editors are grateful for their contributions which cover an unusually comprehensive compendium of subjects relating to the disease.

Graves' Disease - Pathogenesis and Treatment (Paperback, Softcover reprint of the original 1st ed. 2000): Basil Rapoport,... Graves' Disease - Pathogenesis and Treatment (Paperback, Softcover reprint of the original 1st ed. 2000)
Basil Rapoport, Sandra M. McLachlan
R4,357 Discovery Miles 43 570 Ships in 10 - 15 working days

From the perspective of the investigator, Graves' disease is a fascinating disorder with unique features and opportunities for study. The discovery in 1956 that Graves' disease was caused by a humoral factor, later shown to be an antibody to the TSH receptor, was a triumph for modern investigative medicine. Rapid progress is now being made in (i) understanding the molecular interaction between autoantibodies and the TSH receptor, (ii) identifying the genes that contribute to the predisposition to disease, (iii) developing an animal model of Graves' disease, and (iv) identifying the long-sought orbital antigen in ophthalmopathy. From the clinical standpoint, although Graves' disease is eminently treatable, there is no definitive cure. None of the therapeutic options are ideal. It is hoped that rapid progress in understanding the pathogenesis of the disease will lead to the ultimate goal of some form of immunotherapy that will make antithyroid drugs, radioiodine and thyroidectomy obsolete. The chapters in Graves' Disease: Pathogenesis and Treatment represent the viewpoints of many prominent clinicians and investigators working in the field. The editors are grateful for their contributions which cover an unusually comprehensive compendium of subjects relating to the disease.

Free Delivery
Pinterest Twitter Facebook Google+
You may like...
Manufacturing of Nanocomposites with…
Vikas Mittal Hardcover R4,666 Discovery Miles 46 660
Resonance - Long-Lived Waves
Leonard Dobrzynski, Housni Al-Wahsh, … Paperback R4,171 Discovery Miles 41 710
Closing The Gap - The Fourth Industrial…
Tshilidzi Marwala Paperback R600 Discovery Miles 6 000
Winged Messenger - Running Your First…
Bruce Fordyce Paperback  (1)
R331 Discovery Miles 3 310
Principles of Biomedical Informatics
Ira J. Kalet Ph.D. Hardcover R1,852 Discovery Miles 18 520
Sweat Scale Sell - Build Your Business…
Pavlo Phitidis Paperback R320 R290 Discovery Miles 2 900
A Rhetoric of the People - The German…
William E. Coleman, Jr., William E. Coleman, Sr. Hardcover R2,199 Discovery Miles 21 990
Practical Instruction in Animal…
Joseph Philippe Francois Deleuze Paperback R526 Discovery Miles 5 260
Advocacy Groups and the Entertainment…
Michael Suman, Gabriel Rossman Hardcover R2,218 Discovery Miles 22 180
Experimental Methods in Orthopaedic…
Radovan Zdero Hardcover R3,251 Discovery Miles 32 510

 

Partners