0
Your cart

Your cart is empty

Browse All Departments
  • All Departments
Price
  • R2,500 - R5,000 (2)
  • -
Status
Brand

Showing 1 - 2 of 2 matches in All Departments

Graves' Disease - Pathogenesis and Treatment (Hardcover, 2000 ed.): Basil Rapoport, Sandra M. McLachlan Graves' Disease - Pathogenesis and Treatment (Hardcover, 2000 ed.)
Basil Rapoport, Sandra M. McLachlan
R4,532 Discovery Miles 45 320 Ships in 10 - 15 working days

From the perspective of the investigator, Graves' disease is a fascinating disorder with unique features and opportunities for study. The discovery in 1956 that Graves' disease was caused by a humoral factor, later shown to be an antibody to the TSH receptor, was a triumph for modern investigative medicine. Rapid progress is now being made in (i) understanding the molecular interaction between autoantibodies and the TSH receptor, (ii) identifying the genes that contribute to the predisposition to disease, (iii) developing an animal model of Graves' disease, and (iv) identifying the long-sought orbital antigen in ophthalmopathy. From the clinical standpoint, although Graves' disease is eminently treatable, there is no definitive cure. None of the therapeutic options are ideal. It is hoped that rapid progress in understanding the pathogenesis of the disease will lead to the ultimate goal of some form of immunotherapy that will make antithyroid drugs, radioiodine and thyroidectomy obsolete. The chapters in Graves' Disease: Pathogenesis and Treatment represent the viewpoints of many prominent clinicians and investigators working in the field. The editors are grateful for their contributions which cover an unusually comprehensive compendium of subjects relating to the disease.

Graves' Disease - Pathogenesis and Treatment (Paperback, Softcover reprint of the original 1st ed. 2000): Basil Rapoport,... Graves' Disease - Pathogenesis and Treatment (Paperback, Softcover reprint of the original 1st ed. 2000)
Basil Rapoport, Sandra M. McLachlan
R4,357 Discovery Miles 43 570 Ships in 10 - 15 working days

From the perspective of the investigator, Graves' disease is a fascinating disorder with unique features and opportunities for study. The discovery in 1956 that Graves' disease was caused by a humoral factor, later shown to be an antibody to the TSH receptor, was a triumph for modern investigative medicine. Rapid progress is now being made in (i) understanding the molecular interaction between autoantibodies and the TSH receptor, (ii) identifying the genes that contribute to the predisposition to disease, (iii) developing an animal model of Graves' disease, and (iv) identifying the long-sought orbital antigen in ophthalmopathy. From the clinical standpoint, although Graves' disease is eminently treatable, there is no definitive cure. None of the therapeutic options are ideal. It is hoped that rapid progress in understanding the pathogenesis of the disease will lead to the ultimate goal of some form of immunotherapy that will make antithyroid drugs, radioiodine and thyroidectomy obsolete. The chapters in Graves' Disease: Pathogenesis and Treatment represent the viewpoints of many prominent clinicians and investigators working in the field. The editors are grateful for their contributions which cover an unusually comprehensive compendium of subjects relating to the disease.

Free Delivery
Pinterest Twitter Facebook Google+
You may like...
100+ Years of Plastics - Leo Baekeland…
E. Thomas Strom, Seth Rasmussen Hardcover R5,807 Discovery Miles 58 070
Captain America
Jack Kirby, Joe Simon, … Paperback R610 R308 Discovery Miles 3 080
American Diplomacy and Strategy toward…
S Kim Hardcover R1,534 Discovery Miles 15 340
Resonance - Long-Lived Waves
Leonard Dobrzynski, Housni Al-Wahsh, … Paperback R4,171 Discovery Miles 41 710
Escalation Management in International…
Jonathan Wilkenfeld, Egle E. Murauskaite Hardcover R3,360 Discovery Miles 33 600
Plastics Processing Data Handbook
D. V Rosato Hardcover R5,980 Discovery Miles 59 800
Focus BrE 1 Students' Book…
Marta Uminska, Patricia Reilly Paperback R1,756 Discovery Miles 17 560
The Works of Dr. Jonathan Swift…
Jonathan Swift Paperback R677 Discovery Miles 6 770
Rise and Shine American Starter…
Helen Dineen Digital product license key R1,097 Discovery Miles 10 970
Collaborative Networks for a Sustainable…
Luis M. Camarinha-Matos, Xavier Boucher, … Hardcover R3,052 Discovery Miles 30 520

 

Partners