Darwin's theory of evolution by natural selection was based on the observation that there is variation between individuals within the same species. This fundamental observation is a central concept in evolutionary biology. However, variation is only rarely treated directly. It has remained peripheral to the study of mechanisms of evolutionary change. The explosion of knowledge in genetics, developmental biology, and the ongoing synthesis of evolutionary and developmental biology has made it possible for us to study the factors that limit, enhance, or structure variation at the level of an animals' physical appearance and behavior. Knowledge of the significance of variability is crucial to this emerging synthesis. This volume situates the role of variability within this broad framework, bringing variation back to the center of the evolutionary stage.
-Provides an overview of current thinking on variation in evolutionary biology, functional morphology, and evolutionary developmental biology
-Written by a team of leading scholars specializing on the study of variation
-Reviews of statistical analysis of variation by leading authorities
-Key chapters focus on the role of the study of phenotypic variation for evolutionary, developmental, and post-genomic biology

Illuminating the processes and patterns that link genotype to phenotype, "Epigenetics" seeks to explain features, characters, and developmental mechanisms that can only be understood in terms of interactions that arise above the level of the gene. With chapters written by leading authorities, this volume offers a broad integrative survey of epigenetics. Approaching this complex subject from a variety of perspectives, it presents a broad, historically grounded view that demonstrates the utility of this approach for understanding complex biological systems in development, disease, and evolution. Chapters cover such topics as morphogenesis and organ formation, conceptual foundations, and cell differentiation, and together demonstrate that the integration of epigenetics into mainstream developmental biology is essential for answering fundamental questions about how phenotypic traits are produced.