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Electroanalysis in Biomedical and Pharmaceutical Sciences - Voltammetry, Amperometry, Biosensors, Applications (Hardcover, 1st ed. 2015)
Sibel A Ozkan, Jean-Michel Kauffmann, Petr Zuman; Contributions by Ana Maria Oliveira Brett, Christopher Brett, …
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Discovery Miles 37 590
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Through this monograph, the pharmaceutical chemist gets familiar
with the possibilities electroanalytical methods offer for
validated analyses of drug compounds and pharmaceuticals. The
presentation focuses on the techniques most frequently used in
practical applications, particularly voltammetry and polarography.
The authors present the information in such a way that the reader
can judge whether the application of such techniques offers
advantages for solving a particular analytical problem. Basics of
individual electroanalytical techniques are outlined using as
simple language as possible, with a minimum of mathematical
apparatus. For each electroanalytical technique, the physical and
chemical processes as well as the instrumentation are described.
The authors also cover procedures for the identification of
electroactive groups and the chemical and electrochemical processes
involved. Understanding the principles of such processes is
essential for finding optimum analytical conditions in the most
reliable way. Added to this is the validation of such analytical
procedures. A particularly valuable feature of this book are
extensive tables listing numerous validated examples of practical
applications. Various Indices according to the drug type, the
electroactive group and the type of method as well as a subject and
author index are also provided for easy reference.
Biosensors: Fundamentals, Emerging Technologies, and Applications
provides insight into the sensing applications of different types
of biosensors relating to environmental pollutants, microbiological
analysis, and healthcare. It describes state-of-the-art research in
biosensors, point of care testing, potential applications, as well
as future prospects for biosensors. This book: Presents the
essentials that readers need to know to make full use of biosensor
technology Discusses recent perspectives on optical and
electrochemical biosensors Details biosensor types for medical
applications Teaches how to use enzymes for biological recognition
in biomarker assays Proposes innovations in wearable and smart
biosensors This book is aimed at advanced students, researchers,
and academics across a broad interdisciplinary field including
biochemical, pharmaceutical, and environmental engineering as well
as materials science, analytical chemistry, and biosciences.
Through this monograph, the pharmaceutical chemist gets familiar
with the possibilities electroanalytical methods offer for
validated analyses of drug compounds and pharmaceuticals. The
presentation focuses on the techniques most frequently used in
practical applications, particularly voltammetry and polarography.
The authors present the information in such a way that the reader
can judge whether the application of such techniques offers
advantages for solving a particular analytical problem. Basics of
individual electroanalytical techniques are outlined using as
simple language as possible, with a minimum of mathematical
apparatus. For each electroanalytical technique, the physical and
chemical processes as well as the instrumentation are described.
The authors also cover procedures for the identification of
electroactive groups and the chemical and electrochemical processes
involved. Understanding the principles of such processes is
essential for finding optimum analytical conditions in the most
reliable way. Added to this is the validation of such analytical
procedures. A particularly valuable feature of this book are
extensive tables listing numerous validated examples of practical
applications. Various Indices according to the drug type, the
electroactive group and the type of method as well as a subject and
author index are also provided for easy reference.
Quantum dots (QDs) are hybrid organic/inorganic nanoparticles with
novel physical properties. QDs have two components: an inorganic
core and an optically active coated shell. Moreover, surface
coatings can be applied to QDs to modify the particle as needed for
experiments. Hydrophilic coatings prevent leaking of metal cargo
from the core, enhancing the solubility in biological contexts and
bind molecules, such as receptor-ligands, antibodies, therapeutic,
and diagnostic macromolecules for enhanced effects. Their high
surface-to-volume ratio allows multiple functional groups to attach
onto the surface of the particles at constant surface volume.
Silicon-, gallium-, indium-, or germanium-based; cadmium-based; and
carbon-based QDs have already been used in many applications, such
as imaging probes for the engineering of multifunctional
nanodevices. Superior properties of QDs make them an excellent
system in technology and biotechnology. This book describes
electroanalytical applications of QD-based nanobiosensors,
including brief information about the synthesis and
characterization of QDs and basics of electroanalytical methods,
followed by QDs in electrochemical biomimetic sensors, QDs in
microchips, inorganic materials doped QDs, QD-based electrochemical
DNA biosensors, electroluminescence for biomarker analysis using
aptamer-based QDs, QD-based photoelectrochemical techniques,
enzyme-based nanobiosensors using QDs, QD-based electrochemical
immunosensors, and QD-modified nanosensors in drug analysis.
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