Laudato Si’ insists on a revolutionary human response to the public challenges of our time concerning the ecological crisis. The volume takes up the revolutionary spirit of Pope Francis and speaks to the economic, technological, political, educational, and religious changes needed to overcome the fragile relationships between humans and Earth. This volume identifies various systemic factors that have produced the anthropogenic ecological crisis that threatens the planet and uses the ethical vision of Laudato Si’ to promote practical responses that foster fundamental changes in humanity’s relationships with Earth and each other. The essays address not only the immediate behavioral changes needed in individual human lives, but also the deeper, societal changes required if human communities are to live sustainable lives within Earth’s integral ecology. Thus, this volume intentionally focuses on a plurality of cultural contexts and proposes solutions to problems encountered in a variety of global contexts. Accordingly, the contributors to this volume are scholars from a breadth of interdisciplinary and cultural backgrounds, each exploring an ethical theme from the encyclical and proposing systemic changes to address deeply entrenched injustices. Collectively, their essays examine the social, political, economic, gender, scientific, technological, educational, and spiritual challenges of our time as these relate to the ecological crisis.