It has been recognized for many years that cancers originating in the breast and prostate gland are frequently 'endocrine-dependent. ' Traditional thera pies included surgical endocrine ablative procedures or pharmacologic hor mone administration, both designed to antagonize the stimulatory effects of sex steroid hormones. In the past decade, several new treatment strategies for these tumors have emerged from basic studies in reproductive biology and mechanisms of action of steroid hormones. In some instances, these new treatments have elimin ated or reduced the need for major surgical ablative procedures or for toxic hormone therapy. The clinical role for other new treatments has not yet been clearly defined, although exciting preliminary data from recent clinical trials are now available. Thus, an objective review of the current status of these new therapeutic approaches is of interest. In this volume we have attempted to provide an in-depth review of both basic and clinical research involving several new treatment strategies for breast and prostate cancer. The first three chapters summarize preclinical and clinical studies of the luteinizing hormone-releasing hormone analogues, which can be used effectively to induce 'medical castration. ' Chapters 4, 5, and 6 review the rationale and clinical use of the compounds known collec tively as the aromatase inhibitors, which can also be used to suppress sex steroid hormone levels. Antiestrogen mechanism of action and its clinical implications for the design of innovative treatment approaches is considered in chapters 7 and 8."

It has been recognized for many years that cancers originating in the breast and prostate gland are frequently 'endocrine-dependent. ' Traditional thera pies included surgical endocrine ablative procedures or pharmacologic hor mone administration, both designed to antagonize the stimulatory effects of sex steroid hormones. In the past decade, several new treatment strategies for these tumors have emerged from basic studies in reproductive biology and mechanisms of action of steroid hormones. In some instances, these new treatments have elimin ated or reduced the need for major surgical ablative procedures or for toxic hormone therapy. The clinical role for other new treatments has not yet been clearly defined, although exciting preliminary data from recent clinical trials are now available. Thus, an objective review of the current status of these new therapeutic approaches is of interest. In this volume we have attempted to provide an in-depth review of both basic and clinical research involving several new treatment strategies for breast and prostate cancer. The first three chapters summarize preclinical and clinical studies of the luteinizing hormone-releasing hormone analogues, which can be used effectively to induce 'medical castration. ' Chapters 4, 5, and 6 review the rationale and clinical use of the compounds known collec tively as the aromatase inhibitors, which can also be used to suppress sex steroid hormone levels. Antiestrogen mechanism of action and its clinical implications for the design of innovative treatment approaches is considered in chapters 7 and 8."

Toxicology—the scientific study of environmental factors that are harmful to living organisms—was established more than 400 years ago by the Swiss physician Paracelsus. Yet, despite its long lineage, this fascinating discipline continues to evolve sophisticated new tools and techniques for identifying toxins and the means by which they impair health.

This book provides environmental technology students with an enjoyable and effective way to acquire the solid working knowledge of toxicology basics they'll need to make informed decisions as professionals. Features that make Basics of Toxicology an ideal introduction to the subject for two-year and four-year environmental technology students, include:

• Acclaimed, user-friendly, modular format found in all the books in the Preserving the Legacy series
• Basic anatomy, physiology, and chemistry concepts that help clarify how toxins interact with living tissue
• Rapid-learning chapter structure, featuring clear, concise objectives, concept statements, and summaries, as well as practice questions
• Helpful sidebars that highlight critical concepts
• More than 150 high-quality line-drawings, photographs, diagrams, charts, and tables
• Numerous easy-to-perform, skill-building activities
• A glossary of more than 800 essential terms
• Extensive bibliography of recommended readings in all key subject areas
• Basic anatomy, physiology, and chemistry concepts that help clarify how toxins interact with living tissue

Its comprehensive scope along with its quick-reference design also makes Basics of Toxicology a handy working reference for practicing environmental technicians.

This book was written to inspire hope and to begin healing for those experiencing adversity or who have wounds to heal. I hope that my words help you gain perspective on the past and avoid the mistakes I've made as you go forward on your journey. I now view every single experience as positive because adversity brought me here--to this place where I can help you heal your life. This book is dedicated to:

- Rape victims--When they tell you it wasn't your fault, it is true No matter what choices you made, the instant the word "no" crossed your lips, all should have stopped. Whatever happened after that was not your fault. - Those suffering from depression and/or PTSD--As a society, we need to do more to remove the stigma of psychological illness so that more people will seek the help they need, before the situation becomes desperate. - All fibromyalgia patients--We must continue to advocate for a cure and not settle for lifelong symptom management. When we put our voices together, there is nothing we cannot accomplish. - Those who want a change in their life--Whether it's a divorce, an illness, or any other issue that has you feeling "less than," you can change your circumstances. - Anyone who has had, or is having, thoughts of suicide--Know that suicide not the answer. I am an example of that. If I'd not seen that "dark place" and lived to talk about it, I wouldn't be writing this for you today. I would never have known life could be this incredible.

Much has been written about World War II, the reign of Adolph Hitler, and the persecution and annihilation of the Jewish people. But what happened in Germany after the war? In "The Occupation of Germany, 1945-1949," author C. Kent Palmer provides a firsthand account of the duties of the US troops in Germany following the conclusion of the war. The task was to keep Germany safe and secure and to assist in the rebuilding process.

Palmer, who served with the US Army Military Police, describes Germany at that time as the Wild West of America. He explains the environment in which the young soldiers operated, presents some of the threats and dangers with which they were presented, and discusses some of the unique situations that occurred including stories about off-duty freedoms.

Part history, part memoir, "The Occupation of Germany, 1945-1949" offers the firsthand viewpoint of one young American solider who served his country while helping another country to restructure after being defeated in a terrible war.

The University of Kansas (KU) is a public research university and the largest university in the state of Kansas. Created by the staff of the KU libraries, KU ScholarWorks is the digital repository of the University. It contains scholarly work created by KU faculty and staff, as well as material from the University Archives. KU ScholarWorks makes important research and historical items available to a wider audience and helps assure their long-term preservation. The University of Kansas's KU ScholarWorks Pre-1923 Theses and Dissertation collection was digitized by the Scholarly Communications program staff in the KU Libraries' Center for Digital Scholarship. These theses and dissertations range from 1883 - 1921 and reflect topics from Engineering and History to Economics and Chemistry, including titles like A Study of Terpeneless Lemon Extracts, English Interest in the Abolition of the Slave Trade, and Aspects of the Gothic Romance.

A volume in The Achievement Gap, Research, Practice, and Policy C. Kent McGuire and Vivian W. Ikpa, Series Editors This is the second book in the series examining student achievement. The chapters in this book reflect the scholarly papers presented at the July 2006 Education Policy, Leadership Summer Institute (EPLSI) by K-16 educators, researchers, community advocates, and policymakers who work in urban communities. The Institute serves as a place where individuals interested in scholarly discussions and research directly related to: (1) how data can be utilized to inform policy; (2) examining the urban school context from the perspectives of the polity, school leaders; students; and other related internal and external actors; and (3) identifying strategies for improving student academic achievement can gather. During this week-long Institute, participants examined the structural problems and policy tensions affecting urban communities and student achievement. The Institute's theme, Meeting the Challenges of Urban Schools is reflected throughout this book. Specifically, this edition explores the interrelated aspects of policy, practice and research and how they affect academic achievement. The five sections in this book examine different challenges facing urban schools and their impact on student performance.

A volume in The Achievement Gap, Research, Practice, and Policy C. Kent McGuire and Vivian W. Ikpa, Series Editors This is the second book in the series examining student achievement. The chapters in this book reflect the scholarly papers presented at the July 2006 Education Policy, Leadership Summer Institute (EPLSI) by K-16 educators, researchers, community advocates, and policymakers who work in urban communities. The Institute serves as a place where individuals interested in scholarly discussions and research directly related to: (1) how data can be utilized to inform policy; (2) examining the urban school context from the perspectives of the polity, school leaders; students; and other related internal and external actors; and (3) identifying strategies for improving student academic achievement can gather. During this week-long Institute, participants examined the structural problems and policy tensions affecting urban communities and student achievement. The Institute's theme, Meeting the Challenges of Urban Schools is reflected throughout this book. Specifically, this edition explores the interrelated aspects of policy, practice and research and how they affect academic achievement. The five sections in this book examine different challenges facing urban schools and their impact on student performance.

How does one rise above oneself? What does transcending mean and what does it entail? Transcending hate, envy, revenge, and other destructive emotions in order to reach a higher self, conveys to some the idea that this is of a spiritual experience more appropriate for mystics or saints than for ordinary people. However, this is not the case. This book will show that transcending does not require sainthood but, rather, a clear understanding of what transcending involves.

This contributor volume brings the best work of such established historians as Morris Schappes, Nathan Godfried, and Eric Foner together with the newer voices of Elizabeth Sharpe and Jennifer Bosch. Its eleven essays challenge the boundary between the older, institutional labor history and the more recent social histories of working people. By combining a focus on culture, women's history, and race relations that is characteristic of the best of the latest working class history with an emphasis on formal protests, leadership, and power, the volume suggests that a truly new labor history will reflect a variety of concerns and draw on diverse inspirations. In three chapters elucidating new features of labor biography and working-class politics, the volume's opening section considers George Edwin McNeill, the Socialist Party's efforts to free Eugene Debs, and the Socialist Party's left wing. Turning to women in labor history, the next section includes two chapters on Union W.A.G.E., an organization of mainly white, working class women, and Ellen Gates Starr, co-founder of Hull House. In a third section on African-American history, two scholars consider Black labor and African-American laborers in the Reconstruction era. The final section considers culture, education, and the working class. These chapters analyze the role of broadcasting and the Socialists' effort to establish an alternative radio station; labor education in the 1920s; the literary portrayal of sailors in Dana's Two Years Before the Mast, and the victims of the Rapp-Coudert Committee. By placing workers and their organizations convincingly within the context of their culture, this volume helps to demonstrate the ways the labor movement has remade this nation and how the nation has shaped the labor movement.