Big Mechanisms in Systems Biology: Big Data Mining, Network Modeling, and Genome-Wide Data Identification explains big mechanisms of systems biology by system identification and big data mining methods using models of biological systems. Systems biology is currently undergoing revolutionary changes in response to the integration of powerful technologies. Faced with a large volume of available literature, complicated mechanisms, small prior knowledge, few classes on the topics, and causal and mechanistic language, this is an ideal resource. This book addresses system immunity, regulation, infection, aging, evolution, and carcinogenesis, which are complicated biological systems with inconsistent findings in existing resources. These inconsistencies may reflect the underlying biology time-varying systems and signal transduction events that are often context-dependent, which raises a significant problem for mechanistic modeling since it is not clear which genes/proteins to include in models or experimental measurements. The book is a valuable resource for bioinformaticians and members of several areas of the biomedical field who are interested in an in-depth understanding on how to process and apply great amounts of biological data to improve research.

This book constitutes the proceedings of the 13th International Conference on Wireless Algorithms, Systems, and Applications, WASA 2018, held in Tianjin, China, in June 2018. The 59 full papers and 18 short papers presented in this book were carefully reviewed and selected from 197 submissions. The papers cover various topics such as cognitive radio networks; wireless sensor networks; cyber-physical systems; distributed and localized algorithm design and analysis; information and coding theory for wireless networks; localization; mobile cloud computing; topology control and coverage; security and privacy; underwater and underground networks; vehicular networks; internet of things; information processing and data management; programmable service interfaces; energy-efficient algorithms; system and protocol design; operating system and middle-ware support; and experimental test-beds, models and case studies.