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The erythrocyte is perhaps the world's single best known cell, an
opinion affirmed by its inseparable linkage with the French
expression "Le sang c'est la vie" (i.e., Blood is life). The red
cell made its debut in a few invertebrates and thereupon conducted
a conceptual phylogenetic odyssey through the Classes of
poikilothermic vertebrates, onward to the first homeotherms the
avians, and thereafter to the mammals including man. The
erythrocyte presents morphologic, cytochemical and quantitative
adaptations as it progresses through its evolutionary continuum.
The specific objective of this text is to explore in depth the
cytology of the erythrocyte in birds. It is intended to derive an
understanding of the red cell's diverse aspects as presented among
Orders, Families and Genera of avians. Illustrative of the subjects
that are explored are the light microscopy and ulrastructure of the
maturational sequence of the erythrocyte from proerythroblast to
the mature cell, the quantitative representation of the erythroid
progenitors in hemopoietic bone marrow, and the relationship of
erythropoiesis with the vascular sinuses in the bone marrow.
Sections are devoted to the quail-chick chimera and the insight it
offers, erythroleukemia, embryologic considerations, primitive and
definitive generation erythrocytes, rbc life span, the impact of
sporozoan parasitization upon the erythrocellular profile and the
morphology associated with pathologic agents and conditions. A
major segment of the monograph is a taxonomically organized Table
of Erythrogramic Data (primary source-cited, and when derived,
indicators of significant differences between sexes, physiologic
and experimental conditions).
Erythrocytes of the Rhesus and Cynomolgus Monkeys addresses the
morphologic, quantitative, and generative aspects of the
erythrocytes of the rhesus monkey Macaca mulatta and the cynomolgus
monkey Macaca fascicularis (long-tailed macaque, crab-eating
monkey). These two species are the most commonly selected nonhuman
primates for basic science and clinical medical investigations. The
hemopoietic cells of man and the rhesus monkey display an intimate
homogeneity. Their functional activities are close and at times
identical. The cynomolgus monkey was enlisted in biomedical studies
at a time when rhesus monkeys were not available in sufficient
quantities. It has gained increased use in the Far East and in the
Western world. It is, for example, employed in the current
development of a vaccine against the deadly Ebola virus. The
authors of the book discuss the erythropoietic profiles of normal
and abnormal macaques of both sexes and of all age groups as
investigated with contemporary electronic methodologies. They cover
the role of stress as it is perceived by the monkey and how it
impacts erythrocellular values, and how to train the monkey to be a
cooperative, unperturbed subject for hematologic study. Additional
topics include the role of medication in deriving normal
physiologic erythrocellular data, the development of the precursors
of the erythrocyte (normoblasts), the morphologic analysis of the
megaloblastic series of abnormal erythroid cells, the analysis of
erythropoiesis in bone marrow, the relationship of the simian
immunodeficiency virus and erythropoiesis, erythrocyte life span,
and parasitic invasion of the red cell.
Erythrocytes of the Rhesus and Cynomolgus Monkeys addresses the
morphologic, quantitative, and generative aspects of the
erythrocytes of the rhesus monkey Macaca mulatta and the cynomolgus
monkey Macaca fascicularis (long-tailed macaque, crab-eating
monkey). These two species are the most commonly selected nonhuman
primates for basic science and clinical medical investigations. The
hemopoietic cells of man and the rhesus monkey display an intimate
homogeneity. Their functional activities are close and at times
identical. The cynomolgus monkey was enlisted in biomedical studies
at a time when rhesus monkeys were not available in sufficient
quantities. It has gained increased use in the Far East and in the
Western world. It is, for example, employed in the current
development of a vaccine against the deadly Ebola virus. The
authors of the book discuss the erythropoietic profiles of normal
and abnormal macaques of both sexes and of all age groups as
investigated with contemporary electronic methodologies. They cover
the role of stress as it is perceived by the monkey and how it
impacts erythrocellular values, and how to train the monkey to be a
cooperative, unperturbed subject for hematologic study. Additional
topics include the role of medication in deriving normal
physiologic erythrocellular data, the development of the precursors
of the erythrocyte (normoblasts), the morphologic analysis of the
megaloblastic series of abnormal erythroid cells, the analysis of
erythropoiesis in bone marrow, the relationship of the simian
immunodeficiency virus and erythropoiesis, erythrocyte life span,
and parasitic invasion of the red cell.
The erythrocyte is perhaps the world's single best known cell, an
opinion affirmed by its inseparable linkage with the French
expression "Le sang c'est la vie" (i.e., Blood is life). The red
cell made its debut in a few invertebrates and thereupon conducted
a conceptual phylogenetic odyssey through the Classes of
poikilothermic vertebrates, onward to the first homeotherms the
avians, and thereafter to the mammals including man. The
erythrocyte presents morphologic, cytochemical and quantitative
adaptations as it progresses through its evolutionary continuum.
The specific objective of this text is to explore in depth the
cytology of the erythrocyte in birds. It is intended to derive an
understanding of the red cell's diverse aspects as presented among
Orders, Families and Genera of avians. Illustrative of the subjects
that are explored are the light microscopy and ulrastructure of the
maturational sequence of the erythrocyte from proerythroblast to
the mature cell, the quantitative representation of the erythroid
progenitors in hemopoietic bone marrow, and the relationship of
erythropoiesis with the vascular sinuses in the bone marrow.
Sections are devoted to the quail-chick chimera and the insight it
offers, erythroleukemia, embryologic considerations, primitive and
definitive generation erythrocytes, rbc life span, the impact of
sporozoan parasitization upon the erythrocellular profile and the
morphology associated with pathologic agents and conditions. A
major segment of the monograph is a taxonomically organized Table
of Erythrogramic Data (primary source-cited, and when derived,
indicators of significant differences between sexes, physiologic
and experimental conditions).
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