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This book presents recent advances in and perspectives on the use
of organoselenium compounds, primarily highlighting the new
frontiers in the field of Green Chemistry, their therapeutic and
biological relevance and new materials. Throughout its 200 pages,
readers will find an updated and comprehensive review of new
aspects of organoselenium chemistry and biochemistry. Fully
referenced and written in an easy to read style, it offers readers
a primary resource for including organoselenium derivatives in
their projects. This book will be of interest to specialists,
students and researchers involved in a broad range of fields, from
synthetic green chemistry to medicinal chemistry and the chemistry
of natural products. The connection between organoselenium
compounds and green chemistry, despite having only recently
emerged, is one of the subjects of this book. The first chapter
highlights the use of Se-containing molecules as reagents and
catalysts in new green protocols to access important organic
transformations. The book provides a wealth of examples of
bioactive Se-containing molecules, especially focusing on those
with potential therapeutic uses. The second chapter focuses on the
state of the art concerning the role of organoselenium compounds as
antioxidants, GPx mimics, and derivatives endowed with different
bioactive properties. "Organoselenium in nature" is the title of
the third chapter, which equips readers with essential information
on the main natural organoselenium compounds and where they are
found. Selected aspects of the metabolism of selenium in plants and
microorganisms are also discussed. In closing, the book includes a
chapter dedicated to recent advances concerning the nonbonding
interactions between organochalcogen compounds. This is currently a
hot topic in selenium chemistry and biochemistry, and here readers
will find key insights into the chalcogen bond and its role in the
biological activity of organoselenium compounds.
This book presents recent advances in and perspectives on the use
of organoselenium compounds, primarily highlighting the new
frontiers in the field of Green Chemistry, their therapeutic and
biological relevance and new materials. Throughout its 200 pages,
readers will find an updated and comprehensive review of new
aspects of organoselenium chemistry and biochemistry. Fully
referenced and written in an easy to read style, it offers readers
a primary resource for including organoselenium derivatives in
their projects. This book will be of interest to specialists,
students and researchers involved in a broad range of fields, from
synthetic green chemistry to medicinal chemistry and the chemistry
of natural products. The connection between organoselenium
compounds and green chemistry, despite having only recently
emerged, is one of the subjects of this book. The first chapter
highlights the use of Se-containing molecules as reagents and
catalysts in new green protocols to access important organic
transformations. The book provides a wealth of examples of
bioactive Se-containing molecules, especially focusing on those
with potential therapeutic uses. The second chapter focuses on the
state of the art concerning the role of organoselenium compounds as
antioxidants, GPx mimics, and derivatives endowed with different
bioactive properties. "Organoselenium in nature" is the title of
the third chapter, which equips readers with essential information
on the main natural organoselenium compounds and where they are
found. Selected aspects of the metabolism of selenium in plants and
microorganisms are also discussed. In closing, the book includes a
chapter dedicated to recent advances concerning the nonbonding
interactions between organochalcogen compounds. This is currently a
hot topic in selenium chemistry and biochemistry, and here readers
will find key insights into the chalcogen bond and its role in the
biological activity of organoselenium compounds.
Organochalcogen compounds reviews the state of the art in new green
protocols involving organochalcogen compounds (Se, S, and Te),
including the use of nonconventional reaction media, alternative
solvents, and solvent-free protocols to prepare these important
compounds. Bringing together several leading researchers in
organochalcogen chemistry, it provides an authoritative overview of
the current state of the field and compiles recent advances in
methodologies for the application of green chemistry principles in
compound development. These include the use of organochalcogen
compounds as intermediates, catalysts, or target products across a
range of applications. The recent developments outlined in in the
book reflect the efforts of the researchers in this area to move
toward a more sustainable chemistry, giving the book the dual
benefit of highlighting the latest developments in the field while
also showing how the principles of green chemistry can effectively
be included in active research projects. Thus it is a valuable
reference for chemists, particularly those working in organic,
green, and synthetic chemistry across both academia and industry.
Up until a few decades ago, chalcogen chemistry was mainly
represented by the chemistry of sulfur-containing compounds.
However, with the rise in research around selenium and tellurium
compound chemistry, the field has developed significantly as it
continues to uncover and understand the peculiarities chalcogens
exhibit. Taking an introductory approach, this book is the
foundation to the subject that has been long needed. Covering
organic and inorganic synthesis, structural properties,
coordination chemistry and computational modelling, all key classes
of chalcogen compounds are illustrated. Applications across
materials science, biology, pharmaceutical science and
environmental topics highlight to readers the impact of chalcogen
chemistry in many aspects of research. Edited by international
leaders in the field, Chalcogen Chemistry brings together
contributions from acclaimed researchers around the world. This
book is ideal for newcomers and established researchers, and
provides the first building block to uncovering this fascinating
field.
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