It is fourteen years since insulin was last reviewed in The Handbook of Ex perimental Pharmacology, in volume 32. The present endeavor is more modest in scope. Volume 32 appeared in two separate parts, each having its own subeditors, and together the two parts covered nearly all areas of insulin pharmacology. Such comprehensiveness seemed impractical in a new volume. The amount of in formation related to insulin that is now available simply would not fit in a reasonable amount of space. Furthermore, for better or worse, scientists have be come so specialized that a volume providing such broad coverage seemed likely in its totality to be of interest or value to very few individuals. We therefore decided to limit the present volume to the following areas: insulin chemistry and structure, insulin biosynthesis and secretion, insulin receptor, and insulin action at the cellular level. We felt these areas formed a coherent unit. We also felt, perhaps as much because of our own interests and perspectives as any objective reality, that these were the areas in which recent progress has been most dramatic, and yet, paradoxically and tantalizingly, these were the areas in which most has yet to be learned. Even with this limited scope, there are some major gaps in coverage. Regrettably, two important areas, the beta cell ATP-sensitive potassium channel and the glucose transporter, were among these. Nevertheless, the authors who con tributed have done an excellent job, and we would like to thank them for their diligence.

Born into a family of pioneering visionaries who helped shape the history of America, W. Scott McLucas, II., grew up the privileged namesake of a prominent Midwest banking mogul. While the nation reeled from the Great Depression and the Second World War, young Scott received the finest private school education and lived in the lap of luxury until, in his senior year at Yale, he was faced with a life-and-death decision that would haunt him for more than three decades. Journey with Scott as he fulfills his duty to his country, pursues a career in advertising, broadcasting, film-making, and theater production, and travels the world, all the while in the grip of a death threat calculated to destroy him. And, finally, celebrate with Scott as he spends the past three decades with the woman he loves by his side and One World Foundation, Inc. as his far-reaching philanthropic arm. Following in the footsteps of his pioneering ancestors, W. Scott McLucas has discovered creative joy in supporting the fields of art, education, Pulitzer-prize winning dance and drama, and environmental preservation.

The second in the I Love to Fish Series, Joseph and his Dad bring home a big Cobia (Brown Bomber), Mom cooks it up, and sister Brooke invites the neighbors to share in the bounty, but not until Joseph learns a lesson about his responsibility as First Mate. A portion from the sale of this book benefits the Pediatric Cancer Foundation.

A failed suicide attempt at age eight left Ingrid with a broken arm but a healing heart. "I didn't die that day, but I wanted to. My mother had tried to sell me again," declares Ingrid Reeves, recalling her dark, desperate youth as the only white child in a mixed-race family. Ingrid lived to triumph over hate, hardship and prejudice. As a wife and mother, the contemporary pioneer woman lived without electricity for twelve years, carving out a Circle of Love sanctuary on a remote mountain in the California wilderness. For thirty years, she wore a hard hat, bravely working in a danger zone by her husband's side to build a business. Today, Ingrid invites you on an amazing journey to a land of bubble magic, beauty and rich bounty. Don your pink hard hat, dive into adventure and taste the sweet nectar of success!

This biography of Josephine Wall, the "Premier Spirit of Imagination Artist," describes the who, what, where and how she creates her art. The book includes personal stories of family members often used in her paintings, personal photographs and 50 of her most popular images. Welcome to the magical world of Josephine's fairies, wizards, godesses, angels and nature spirits In Josephine's Palette of Dreams, you will discover the many faces of the English-born artist as you learn the intimate details of her earthly journey from childhood on. There are many luminous layers abounding with hidden faces in enchanting detail in her imaginative, brilliantly coloured paintings. You will find that Josephine Wall is a passionate, diverse and exceptionally gifted woman whose myriad accomplishments encompass nearly all areas of the artistic as well as human experience. "The art of painting is an all-consuming obsession for me," says Josephine.