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Insulin (Paperback, Softcover reprint of the original 1st ed. 1990)
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Insulin (Paperback, Softcover reprint of the original 1st ed. 1990)
Series: Handbook of Experimental Pharmacology, 92
Expected to ship within 10 - 15 working days
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It is fourteen years since insulin was last reviewed in The
Handbook of Ex perimental Pharmacology, in volume 32. The present
endeavor is more modest in scope. Volume 32 appeared in two
separate parts, each having its own subeditors, and together the
two parts covered nearly all areas of insulin pharmacology. Such
comprehensiveness seemed impractical in a new volume. The amount of
in formation related to insulin that is now available simply would
not fit in a reasonable amount of space. Furthermore, for better or
worse, scientists have be come so specialized that a volume
providing such broad coverage seemed likely in its totality to be
of interest or value to very few individuals. We therefore decided
to limit the present volume to the following areas: insulin
chemistry and structure, insulin biosynthesis and secretion,
insulin receptor, and insulin action at the cellular level. We felt
these areas formed a coherent unit. We also felt, perhaps as much
because of our own interests and perspectives as any objective
reality, that these were the areas in which recent progress has
been most dramatic, and yet, paradoxically and tantalizingly, these
were the areas in which most has yet to be learned. Even with this
limited scope, there are some major gaps in coverage. Regrettably,
two important areas, the beta cell ATP-sensitive potassium channel
and the glucose transporter, were among these. Nevertheless, the
authors who con tributed have done an excellent job, and we would
like to thank them for their diligence.
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