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In recent years, the advancing science and increasing availability
of assisted reproduction have given new hope to infertile couples.
However, the use of IVF and ART has also led to marked increases in
the number of multiple-infant live births. This poses a public
health concern, as these neonates have a higher rate of pre-term
delivery, compromising their survival chances and increasing their
risk of lifelong disability. By optimizing the selection of gametes
and embryos with high probabilities of implantation, it is possible
to reduce the number of embryos transferred and, by extension, the
number of high-risk multiple gestations, while maintaining or
increasing pregnancy rates. Human Gametes and Preimplantation
Embryos: Assessment and Diagnosis provides a broad yet concise
overview of established and developing methodologies for assessment
of gamete and embryo viability in assisted reproduction. This book
elucidates the best practices for precisely selecting viable
specimens based on morphology and cleavage rate and covers the
spectrum of emerging adjunctive technologies for predicting
reproductive potential. The authors present their extensive
knowledge of "omics" approaches (genomics, transcriptomics,
proteomics, and metabolomics), with unbiased delineation of the
associated advantages and potential pitfalls. This valuable
clinical resource is well suited to infertility specialists, Ob/Gyn
physicians, IVF laboratory technicians, and researchers in the
fields of embryology and reproductive medicine.
In recent years, the advancing science and increasing availability
of assisted reproduction have given new hope to infertile couples.
However, the use of IVF and ART has also led to marked increases in
the number of multiple-infant live births. This poses a public
health concern, as these neonates have a higher rate of pre-term
delivery, compromising their survival chances and increasing their
risk of lifelong disability. By optimizing the selection of gametes
and embryos with high probabilities of implantation, it is possible
to reduce the number of embryos transferred and, by extension, the
number of high-risk multiple gestations, while maintaining or
increasing pregnancy rates. Human Gametes and Preimplantation
Embryos: Assessment and Diagnosis provides a broad yet concise
overview of established and developing methodologies for assessment
of gamete and embryo viability in assisted reproduction. This book
elucidates the best practices for precisely selecting viable
specimens based on morphology and cleavage rate and covers the
spectrum of emerging adjunctive technologies for predicting
reproductive potential. The authors present their extensive
knowledge of "omics" approaches (genomics, transcriptomics,
proteomics, and metabolomics), with unbiased delineation of the
associated advantages and potential pitfalls. This valuable
clinical resource is well suited to infertility specialists, Ob/Gyn
physicians, IVF laboratory technicians, and researchers in the
fields of embryology and reproductive medicine.
This book provides the Assisted Reproduction Technologies (ART)
community an update of the fast approaching novel technologies that
may allow improved assessment of the reproductive potential of
sperm, oocytes and embryos. The reader has access to concise
updates on the rapidly developing diagnostic technologies
(genomics, transcriptomics, proteomics and metabolomics) and
morphological methods which may help us better assess the gametes
and embryos. Methodologies are described which enable selection of
the best gamete or embryo by invasive and non-invasive diagnostics,
as well as the clinical validity of these techniques.
Address the future of innovative reproductive technologies with
experts in the fields of IVF, fertility preservation and laboratory
advances. This essential resource examines the changing roles of
IVF, and moves beyond the basics of reproductive medicine. This
book introduces the optimization of care, to improve patient
outcomes, whilst facing ethical challenges that accompany new
technologies, and applying the patient-centered care model to
improve both patient and staff retention. By showcasing the future
of the field in terms of clinical practice and innovative
laboratory technologies, this guide will support clinics worldwide
to provide high-quality customer experience, maintaining a
competitive edge, following increasing standardization of clinical
and laboratory protocols. This invaluable guide features chapters
on patient evaluation, predictive modelling, advances in
pharmacology, and laboratories of the future. Written by research
and clinical leaders from around the world, it describes
ground-breaking innovative treatments and technologies,
encompassing the care model in a holistic way.
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