|
Showing 1 - 25 of
27 matches in All Departments
Neurotransmitters are usually considered to be endogenous
substances that are released from neurons, act on receptor sites
that are typically present on membranes of postsynaptic cells and
produce a functional change in the properties of the target cell.
They are essential features of the nervous systems of all animals
and numerous chemicals can act as neurotransmitters either
intentionally (e.g. pesticides) or unintentionally (neurotoxins).
The most common forms of neurotoxicity are the death of neurons,
degeneration of axons, damage to glial cells and interference with
the axonal membrane or neurotransmission. Important neurotoxins are
found among pesticides, metals, solvents, natural substances, and
industrial chemicals. Environmental chemicals may also contribute
to the pathology of neurodevelopmental, neuropsychiatric, and
neurodegenerative disorders. Neurotransmitters and Toxicology will
be particularly appealing to toxicologists with an interest in
neurotoxicology in a variety of sub-disciplines, as well as
neuro-chemists interested in pathology and disease mechanisms
associated with neurotoxicants.
|
The Coronavirus Pandemic and the Future - Virology, Epidemiology, Translational Toxicology and Therapeutics, Volume 1 (Hardcover)
Michael D Waters, Alok Dhawan, Tim Marrs, Diana Anderson, Stafford Warren, …
|
R4,051
R3,561
Discovery Miles 35 610
Save R490 (12%)
|
Ships in 12 - 17 working days
|
This first volume chronicles the early stages of the outbreak and
world-wide spread of SARS-Cov-2 (COVID-19) and delineates the role
of several disciplines in therapeutic and control measures.
Documenting the epidemiologic response from China, the clinical
evaluation, pathology and intial therapeutics that were available
during the first 6 months and onwards of the outbreak, this book
records how the response to the pandemic was mounted and how
various branches of science and research combined to rapidly expand
our understanding of the disease.
Concerns about the adverse effects of chemicals present in the
environment have created a need for better systems to assess their
potential consequences on human health. One potential solution is
the versatile and state-of-the-art Comet assay. Simple, sensitive,
rapid and visual, this modern toxicological method allows
quantitative and qualitative assessment of DNA damage in single
cells. This assay is used in diverse fields ranging from clinical
applications, human monitoring and environmental toxicology through
to genetic toxicity testing. This updated and revised edition of
The Comet Assay in Toxicology provides the latest information on
this important tool. It addresses, in-depth, the different
protocols, statistical analyses and applications used worldwide. It
also includes the guidelines recommended by the Working Group on
Comet Assay. The book begins with a review of the genesis of the
assay for those new to the technique and goes on to explain
procedures followed to assess different types of DNA damage,
various applications of the assay, and guidelines for the conduct
of the assay in in vitro and in vivo systems. New chapters written
for this edition will provide information on the most contemporary
approaches and applications, including in silico approaches, on
meta-analysis of data and on the application of the Comet Assay in
nanotoxicology. This book will serve as both a reference and a
guide to students as well as investigators in the biomedical,
biochemical and pharmaceutical sciences fields.
The latest attack on Thera Logan's life wasn't the first one and
won't be the last. Someone wants her dead, but until she realizes
that these attacks aren't just random acts of violence or mere
coincidences, she leaves herself wide-open. After her divorce from
Nolan Logan, she decides to move from Seattle, Washington back to
her hometown of Tahlequah, Oklahoma to live with her father and try
to start a new life. She is surprised to find her old childhood
sweetheart, Caleb Sutherland, has moved back home too. Old sparks
fly until Caleb starts asking too many questions, and then the
mystery surrounding Caleb's return coinciding with hers draws her
suspicion. Caleb is determined to get answers to pertinent
questions that he feels only Thera can answer, and he'll go to any
length to get them . . . even deception. He's not the only one
asking too many questions. Her ex-husband pops in for unexpected
visits, wants to reconcile, and is being far too inquisitive.
Confusion fogs Thera's world. What does Caleb really want? Why the
sudden interest from Nolan? And who is stalking her? What does she
possess that is more important to someone than her own life? Her
fears and suspicions of Caleb and Nolan's annoying persistence to
reconcile put her into flight mode, but fleeing will only set into
motion a deadly rollercoaster ride leading up to an event that
leaves her totally helpless. Her only way back is to remember when.
How do you make love to a sleep, busy or exhausted woman? There is
a secret formula a guy can employ so you will want sex anytime he
makes it worth you while. This books tell you how. If you would
like to be ready for your man's sexual advances anytime, day or
night, instead of wondering, "What is he thinking, ? Now is not a
good time," you can learn a few simple secrets to help you be eager
for lovemaking anytime he is ready. This booklet tells you and your
man how to approach intimacy when you are tired, asleep or busy for
great pleasure that both of you will love. Being open and available
increases the connection and strengthens the love between you.
Always in the Mood will generate an unbreakable bond for you and
your man. This direct, short booklet tells how your man can
approach you so that you will never turn him down.
You spend a lot of time in your home and office. These environments
surround you with electronic frequencies that could be out of
harmony with nature and your natural biorhythms. It has only been
in the last one hundred years that human bodies have been subjected
to new and constantly changing frequencies that were absent in most
of our evolution. The imbalance of your indoor environment can
deplete your energy, make you fatigued or even sick. You have the
ability to center yourself within any environment and even bring a
balanced vibration to your indoor living space. The answers to a
healthier indoor setting are within this book. Using this
metaphysical guide to ground yourself and your environment, you can
have the energy and health you desire to feel more alive. Diana
learned at an early age the power of intuition and her
sensitivities to the unseen world. Though touch she was able to
feel the physical pain of others beginning at age seventeen.
Through extensive research and training, she has honed her
intuitive skills and uses them to heal herself and others.
The quiet town of Cypress, Mississippi is turned upside down when a
former citizen, Raven Sawyer, returns for a funeral. Raven's
fictional novel goes viral when the town folk realize that she's
the author, and soon they're thinking that her book is not fiction
but truth. Every little dirty detail is revealed in her book and
has the people of Cypress wagging their tongues and shaking their
heads at a few of the upper-class citizens and-the Sheriff. All
Raven wants is to get through the funeral and go back to New York,
but Sheriff Cal Rayburn can't allow her to leave after she
discovers and turns over evidence that may be connected to a double
homicide that he's investigating. At least, that's the excuse he's
giving her, and he'll go to any length to keep her in Cypress until
he can make her believe that the affair, that she thinks he had six
years ago, never happened. When more dead bodies turn up, Cal feels
they're connected to the double homicide, but with the evidence he
has, he can't make a connection. He's left with more questions than
answers. He's told that Raven's novel may have answers to questions
that could help with his investigation, but what it reveals is more
than what he wants to know. Famous in a Small Town is book one of
An Entering Southern Country Novel trilogy. It has murder, lies,
fiction, and truth-and more twists and turns than the back roads of
northwestern Mississippi. Enter at your own risk.
All orgasms are not created equally. The art of the female climax,
long shrouded in mystery and elusive for many women, is made
accessible in this down-to-earth, illuminating text. Author and
intimacy coach, Diana Anderson presents the essential ingredients
and chemistry necessary to achieve advanced orgasmic experience and
deep connection with your partner. Written with the express purpose
of enhancing women's sex lives and strengthening the bonds in their
relationships, Deep Sex discusses the health-giving pleasures of
sex in simple terms for the modern woman, engaging the reader with
provocative concepts, tips and techniques to enhance love-making.
Filled with specific exercises and penetrating insight, this
straightforward guide to the art of sensuality sheds light on
ancient, little understood concepts like Kundalini energy,
describing many levels of ecstatic sexual embrace and fun ideas to
practice in the bedroom. The book's unpretentious approach to the
many benefits of exceptional sexual climax brings new perspectives
to the potentials of invigorating orgasms and reveals fun climaxes
to reach for in your love life with names like Lightning Bolt
Delight, To the Moon and Back and The Long Country Mile. Deep Sex
is bound to shift your appreciation for the ultimate sensual
moment, enhancing your authentic expression of sensual beauty.
Vanilla Lillian Carver has had her share of disappointment and
heartbreak, from a high school heart throb, to a broken engagement,
and then being left at the altar. She's made up her mind, she's
through with love. Well, that was her plan until the love of her
life returns after disappearing twelve years earlier without even
saying goodbye. Can she trust him again? Her heart says yes, but
common sense says run in the other direction, because there are too
many unanswered questions that she's afraid to ask. Poor Lily She's
running in circles.
Behind your cervix is the deepest place that your partner can
penetrate you. This hidden chamber is called your Fornix, which is
Latin for "vault." Within this treasure are the keys to reaching
your soul, your inner beauty and your creative power. Opening up
fully to your lover -- letting go of inhibitions -- allows him to
reach to this depth within you. Your reward is the best orgasms of
your life and joy that extends into every corner of your world.
Through this level of pleasure and bonding with your lover, you
will access greater personal potential than you ever knew possible.
Learn how to communicate and make love with your man to become
fully aroused and open this deep part of you. Learn about the
different types of orgasm and how to achieve them, including the
Ten Minute Orgasm and the Lightning Bolt Delight Orgasm. Learn how
to trust your man, letting him love you and really see you. When
this happens you radiate far more beauty and truly blossom. Your
Secret Chamber guides you to achieve this. Each chapter offers step
by step "sexercises" to ensure your success. Start today to take
charge of your sexual satisfaction and open to the radiance that is
deep within.
|
Faded Rose (Paperback)
Diana Anderson; Diana Anderson
|
R303
Discovery Miles 3 030
|
Ships in 10 - 15 working days
|
After twelve years of a bad marriage, Rose Daniels makes the
decision to get her life back. A decision that she will be second
guessing after Mother Nature does a number on her, and the murder
of a local woman has Rose's small hometown eyeing her as the
suspect. Rose isn't the prime suspect, she's the only suspect. Only
her faith can save her, but to find that faith, layer upon layer,
of who she has become will have to be peeled away. With what she's
up against, it would be so much easier to give up, but giving up
would be costly. It would cost her, her son and her life.
When Jo Preston Lane was nineteen, she left home thinking that was
the answer to her problem, but now, six years later, she must
return, and who she has to face is the least of her problems. To
protect her family, she must keep all she had discovered five
months ago a secret. She has little time to prepare for her great
escape before her worst nightmare catches up with her. She can't
afford to trust anyone, as her life truly depends on it. Not the
police or the FBI. Mississippi Gambler is the second in A Southern
Country Novel series.
A year ago, Jo Preston was released and sent home from a mental
institution. She has only vague memories of why she had been
committed. Circumstances beyond her control will cause those
memories to surface, one by one. A tragedy, brought on by deceit,
leaves her heartbroken and rejected. She is sent away to live with
some rather peculiar relatives. Her fear of being institutionalized
again has her desperate to keep her past hidden, but how long can
she keep it a secret when her imagination begins playing tricks on
her... or is it? A voice from her past resurfaces as well as the
man who wants her secret to die with her. This is a story about a
young girl's heartbreak, rejection, fear, faith, and determination.
Happy Valley is the first in A Southern Country Novel series.
Your physical condition affects your attitude, outlook on life,
and ability to serve God and others to your full potential. In Fit
for Faith: A Christian Woman's Guide to Total Fitness, author Diana
Anderson provides interesting facts and vital information about
health, nutrition, and exercise, and illustrates the connection
between physical fitness and your walk with Christ.
"Do you not know that your body is a temple of the Holy Spirit, who
is in you, whom you have received from God? You are not your own."
(1 Corinthians 6:19, NIV)
In addition to illustrated step-by-step exercise routines, sample
meal plans, and discussion about the relationship between certain
foods and health taken straight from Scripture, Diana emphasizes
the importance of positive friendships, and the need for rest and
reflection on the Word of God. She also explains the impact of
negative self-talk and stress on your physical condition.
Whether you are a fitness fanatic or a couch potato, Fit for Faith
will meet you right where you are, inspiring you to make lifelong
changes and to adopt a positive attitude toward your health and
physical fitness.
The issue of male germ line mutagenesis and the effects on
developmental defects in the next generation has become
increasingly high profile over recent years. Mutations are thought
to be becoming more prevalent as a result of: exposure to chemicals
in the environment, anti cancer regimes that use genotoxic agents
and assisted conception techniques. In addition to the increasing
frequency of mutations in the general population, attention is also
being given to the effects of epigenetic events on future
generations. Male-mediated Developmental Toxicity discusses these
issues comprehensively and includes further analysis on the
fundamental mechanisms of mutations. With both clinical and
experimental sections, written by leading experts in the field,
this book will appeal to both medical practitioners and
researchers.
This second volume chronicles the later stages of the outbreak of
SARS-Cov-2 (COVID-19) and delineates the role of several
disciplines in therapeutic and control measures highliting the
response from specific coutries of note and efforts to repurpose
and produce new therapeutics and vaccines. By addressing
considerations of efficacy and safety of drugs and chemicals used
to combat COVID-19, virtually in real-time, this book documents and
highlights the advances in science and place the toxicology,
pharmaceutical science, public health and medical community in a
better position to advise in future epidemics.
|
|