Mathematical Methods of Environmental Risk Modeling provides a working introduction to both the general mathematical methods and specific models used for human health risk assessment. Rather than being purely an applied math book, this book focuses on methods and models that students and professionals are likely to encounter in practice. Examples are given from exposure assessment, pharmacokinetic modeling, and dose-response modeling.

Scientists and regulators have struggled to define the role of theory, experiments, models and common sense in risk analysis. This situation has been made worse by the isolation of theory from modeling, of experimentation from theory, and of practical action from basic science. This book arises from efforts at regulatory agencies and industries to bring more science into health risk analysis so that society may better use limited resources to improve public health. This book covers: the characterization of exposure to pollutants and other sources of risk; the movement of pollutants into the body via inhalation; ingestion, dermal absorption, and exposures to radiation; the movement of a pollutant as it cascades through the tissues and organs of the body; and the development of principles and models for dose-response modeling. The book shows how an understanding of the biological, chemical, and physical properties of the environment and of the human body can guide the selection of mathematical models, and how these models can aid in estimating risks. Included in the book are models covering the full range of topics in human health risk analysis: exposure assessment, rates of intake, deposition and uptake by organs, absorption across membranes, biokinetics, dosimetry, and dose-response. The reader will gain from the book a better understanding of how environmental health science, as applied in risk analysis, can be used to create a more rational basis for the improvement of public health.

Risk-Based Environmental Decision: Methods and Culture presents the principles of human health risk analysis as they are applied in environmental decisions. It balances the discussion of scientific theory and methods, philosophical analysis, and applications in regulatory decisions. The material is directed towards risk analysts who must apply their skills in a policy setting, and towards policy analysts who must use risk estimates. The presentation is suited ideally as an introductory text on the methods of risk analysis and on the cultural issues that underlie these methodologies. An important feature of Risk-Based Environmental Decision: Methods and Culture is that it is designed around a series of detailed case studies of environmental risk analysis which walk the reader from the historical nature of the problem, to the formulation as a risk-based problem, to the conduct of risk analysis, and on to the application, debate, and defense of the risk analysis.

Risk-Based Environmental Decision: Methods and Culture presents the principles of human health risk analysis as they are applied in environmental decisions. It balances the discussion of scientific theory and methods, philosophical analysis, and applications in regulatory decisions. The material is directed towards risk analysts who must apply their skills in a policy setting, and towards policy analysts who must use risk estimates. The presentation is suited ideally as an introductory text on the methods of risk analysis and on the cultural issues that underlie these methodologies. An important feature of Risk-Based Environmental Decision: Methods and Culture is that it is designed around a series of detailed case studies of environmental risk analysis which walk the reader from the historical nature of the problem, to the formulation as a risk-based problem, to the conduct of risk analysis, and on to the application, debate, and defense of the risk analysis.

Scientists and regulators have struggled to define the role of theory, experiments, models and common sense in risk analysis. This situation has been made worse by the isolation of theory from modeling, of experimentation from theory, and of practical action from basic science. This book arises from efforts at regulatory agencies and industries to bring more science into health risk analysis so that society may better use limited resources to improve public health. This book covers: the characterization of exposure to pollutants and other sources of risk; the movement of pollutants into the body via inhalation; ingestion, dermal absorption, and exposures to radiation; the movement of a pollutant as it cascades through the tissues and organs of the body; and the development of principles and models for dose-response modeling. The book shows how an understanding of the biological, chemical, and physical properties of the environment and of the human body can guide the selection of mathematical models, and how these models can aid in estimating risks. Included in the book are models covering the full range of topics in human health risk analysis: exposure assessment, rates of intake, deposition and uptake by organs, absorption across membranes, biokinetics, dosimetry, and dose-response. The reader will gain from the book a better understanding of how environmental health science, as applied in risk analysis, can be used to create a more rational basis for the improvement of public health.

Mathematical Methods of Environmental Risk Modeling provides a working introduction to both the general mathematical methods and specific models used for human health risk assessment. Rather than being purely an applied math book, this book focuses on methods and models that students and professionals are likely to encounter in practice. Examples are given from exposure assessment, pharmacokinetic modeling, and dose-response modeling.