This book examines the cogency and value of Nietzsche's idea of eternal recurrence, as an antidote to the nihilism resulting from the catastrophic event of 'the death of God'. Its significance to Nietzsche's philosophy as a whole (when presented either as an imaginative thought experiment, a cosmological hypothesis, or a poetic metaphor) is analysed, alongside the manifold criticisms the idea has attracted. In this original reading of eternal recurrence, McNeil explores the strength of metaphorical meaning contained within Heraclitean and Stoic cosmologies, revealing their influence on Nietzsche's own cosmology, along with their holistic approach to life which Nietzsche endorsed. Furthermore, an extensive critique of Heidegger's interpretation of eternal recurrence is given. McNeil argues that Heidegger ignores not only the life-affirming Dionysian aspects of the concept, but also the Heraclitean sense of play evident in the cosmology, and the importance of this for developing a positive, celebratory attitude towards our lives and creative projects.

In recent years, there have been many exciting breakthroughs in the application of nanotechnology to medicine. In Characterization of Nanoparticles Intended for Drug Delivery, expert researchers explore the latest advances in the field, providing a set of basic methods for the characterization of nanomaterials for medical use. Chapters provide methods to characterize the physiochemical properties (size, aggregation, and surface chemistry) and in vitro immunological and biological characteristics of nanomaterials. Composed in the highly successful Methods in Molecular Biology(TM) series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Comprehensive and informative, Characterization of Nanoparticles Intended for Drug Delivery is an essential survey of methods that are crucial to the preclinical characterization of nanomedicines.

This second edition volume expands on the first edition by providing up-to-date protocols to characterize nanomaterials used as drug delivery agents. The chapters in this book are divided into 5 parts and cover topics such as: advances and obstacles in nanomedicine research; methods to test sterility and endotoxin, physicochemical features, immunological effects, drug release, and in vivo efficacy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Characterization of Nanoparticles Intended for Drug Delivery, Second Edition is a valuable tool for researchers and pharmaceutical and biotechnology developers who are evaluating the clinical potential of nanomedicines in preclinical studies.>

The first collection focused on the writing of provocative author and performance artist Sapphire, including her groundbreaking novel PUSH that has since become the Academy-award-winning film Precious.

This book examines the cogency and value of Nietzsche's idea of eternal recurrence, as an antidote to the nihilism resulting from the catastrophic event of 'the death of God'. Its significance to Nietzsche's philosophy as a whole (when presented either as an imaginative thought experiment, a cosmological hypothesis, or a poetic metaphor) is analysed, alongside the manifold criticisms the idea has attracted. In this original reading of eternal recurrence, McNeil explores the strength of metaphorical meaning contained within Heraclitean and Stoic cosmologies, revealing their influence on Nietzsche's own cosmology, along with their holistic approach to life which Nietzsche endorsed. Furthermore, an extensive critique of Heidegger's interpretation of eternal recurrence is given. McNeil argues that Heidegger ignores not only the life-affirming Dionysian aspects of the concept, but also the Heraclitean sense of play evident in the cosmology, and the importance of this for developing a positive, celebratory attitude towards our lives and creative projects.

This second edition volume expands on the first edition by providing up-to-date protocols to characterize nanomaterials used as drug delivery agents. The chapters in this book are divided into 5 parts and cover topics such as: advances and obstacles in nanomedicine research; methods to test sterility and endotoxin, physicochemical features, immunological effects, drug release, and in vivo efficacy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Characterization of Nanoparticles Intended for Drug Delivery, Second Edition is a valuable tool for researchers and pharmaceutical and biotechnology developers who are evaluating the clinical potential of nanomedicines in preclinical studies.>

In recent years, there have been many exciting breakthroughs in the application of nanotechnology to medicine. In Characterization of Nanoparticles Intended for Drug Delivery, expert researchers explore the latest advances in the field, providing a set of basic methods for the characterization of nanomaterials for medical use. Chapters provide methods to characterize the physiochemical properties (size, aggregation, and surface chemistry) and in vitro immunological and biological characteristics of nanomaterials. Composed in the highly successful Methods in Molecular Biology (TM) series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Comprehensive and informative, Characterization of Nanoparticles Intended for Drug Delivery is an essential survey of methods that are crucial to the preclinical characterization of nanomedicines.

The first collection focused on the writing of provocative author and performance artist Sapphire, including her groundbreaking novel PUSH that has since become the Academy-award-winning film Precious.