An International Conference on the Application of Fracture Mechanics to Ma terials and Structures was held at the Hotel Kolpinghaus in Freiburg, West Ger many, June 20-24, 1983. It was attended by more than 250 participants from different countries which include Austria, Canada, Czechoslovakia, Democratic Republic of Germany, Denmark, Federal Republic of Germany, Finland, France, Greece, Hungary, Israel, Italy, Japan, Netherlands, Norway, People's Republic of China, Portugal, Sweden, Switzerland, United Kingdom, United States of America, USSR and Yugoslavia. Conference Co-Chairmen were Professor G. C. Sih, Lehigh University, Bethle hem, Pennsylvania, U. S. A., Dr. E. Sommer, Fraunhofer-Institut fur Werkstoff mechanik, Freiburg, FRG and Professor W. Dahl, Rheinisch-Westfalische Technische Hochschule, Aachen, FRG. Dr. Wenrich, as the representative of the Land Baden-WUrttemberg, delivered the opening address with the remarks that International Conferences can serve the means to further enhance the technology development of a country. He empha sized that the Federal Republic of Germany is presently in need of strengthening the engineering manpower in order to keep her in a competitive position. The Conference was officially cast off with the leading plenary lectures that under lined the theme of the technical lectures for the first day. This pattern was observed for the five-day meeting. The interplay between material and design re quirements was the theme and emphasized in many of the technical presentations that amounted to approximately ninety (90) papers."

An International Conference on the Application of Fracture Mechanics to Ma terials and Structures was held at the Hotel Kolpinghaus in Freiburg, West Ger many, June 20-24, 1983. It was attended by more than 250 participants from different countries which include Austria, Canada, Czechoslovakia, Democratic Republic of Germany, Denmark, Federal Republic of Germany, Finland, France, Greece, Hungary, Israel, Italy, Japan, Netherlands, Norway, People's Republic of China, Portugal, Sweden, Switzerland, United Kingdom, United States of America, USSR and Yugoslavia. Conference Co-Chairmen were Professor G. C. Sih, Lehigh University, Bethle hem, Pennsylvania, U. S. A. , Dr. E. Sommer, Fraunhofer-Institut fur Werkstoff mechanik, Freiburg, FRG and Professor W. Dahl, Rheinisch-Westfalische Technische Hochschule, Aachen, FRG. Dr. Wenrich, as the representative of the Land Baden-WUrttemberg, delivered the opening address with the remarks that International Conferences can serve the means to further enhance the technology development of a country. He empha sized that the Federal Republic of Germany is presently in need of strengthening the engineering manpower in order to keep her in a competitive position. The Conference was officially cast off with the leading plenary lectures that under lined the theme of the technical lectures for the first day. This pattern was observed for the five-day meeting. The interplay between material and design re quirements was the theme and emphasized in many of the technical presentations that amounted to approximately ninety (90) papers.

This book presents a thorough and critical review of current knowledge on the role of immunology in major psychiatric disorders and its potential applications. The opening chapters offer general information on the immune influence of the brain to provide readers with a better understanding of the end of immune privilege. The book then examines possible underlying mechanisms leading to psychiatric disorders, from early infections to pro-inflammatory markers, stress, and immune genetic background, linking etiology and psychiatry. The third section describes each disorder (ie autism, schizophrenia, bipolar disorder, depression...) with an overview of underlying immune dysfunctions. Lastly, the authors discuss the innovative immune-therapies that may result from the discovery of immune system biomarkers and their associated mechanisms. A better understanding of the role of the immune system in psychiatric disorders makes it possible to identify stratification biomarkers, to explain underlying mechanisms, and to develop innovative, efficient, targeted treatment strategies and management. As such, the book is of value to clinicians, mental health professionals, mental health researchers, immunologists, industry practitioners, and various stakeholders in the mental health field.

This book provides a comprehensive overview of the use of PET and SPECT in the classic psychiatric disorders such as depression, bipolar disorder, anxiety disorders, and schizophrenia. In addition, it discusses the application of these functional neuroimaging techniques in a variety of other conditions, including sleep disorders, eating disorders, autism, and chronic fatigue syndrome. The new edition has been extensively revised and updated to reflect the latest advances and results in nuclear imaging within the field. Most chapters are written jointly by a clinical psychiatrist and a nuclear medicine expert to ensure a multidisciplinary approach. This state of the art compendium will be of value for all who have an interest in the field of neuroscience, from psychiatrists and radiologists/nuclear medicine specialists to interested general practitioners and cognitive psychologists. Companion volumes on the use of PET and SPECT in neurology and for the imaging of neurobiological systems complete a trilogy.

Sicherheit und Verfugbarkeit sind unabdingbare Eigenschaften moderner technischer Anlagen und Konstruktionen. Konzepte fur ihre Bewertung mussen den - aus Grunden des Fortschritts, der Wirtschaftlichkeit und der Umweltpolitik - standig steigenden Anforderungen gewachsen sein. Die vor I iegende Arbeit ver- sucht, zur Weiterentwicklung derartiger Bewertungskonzepte beizutragen. Ein Konzept, das die mechanische Sicherheit von Bauteilen gewahr- leisten soll, hat ublicherweise den vollstandigen Ausschluss eines Versagens zum Ziel. Die Bewertbarkeit von Versagensvorgangen ist hierfur eine notwendige Voraussetzung. Die Schwierigkeit bei der Aufstellung von Bewertungskonzepten besteht darin, den Versagens- prozess charakterisierende Beanspruchungsgroessen und -kriterien zu finden. Erst die Konzepte der Bruchmechanik genugen diesem An- spruch: die Versagensausloesung wird auf ein Zusammenwirken oertlicher Beanspruchungsbedingungen und Werkstoffeigenschaften in der Umgebung von Fehlerstellen zuruckgefuhrt. Fehlerstellen, denen in der Technik eine besondere Bedeutung zukommt, sind Oberflachenfehler, weil Oberflachen von Bauteilen und Komponenten herstellungs-, fertigungs- und einsatzbedingt den meisten Schadein- flussen ausgesetzt sind. Die Methoden der Bruchmechanik haben in den vergangenen Jahr- zehnten fur die quantitative Beschreibung von Versagensvorgangen eine Reihe neuer Zugange und Moeglichkeiten eroeffnet. Ihre Loesungs- ansatze fussen auf den - kontinuumsmechanisch fur einen Bruchprozess relevanten - Parametern, weisen aber wegen der Vielzahl moeglicher Einflussgroessen einen hohen Abstraktionsgrad auf. Deshalb zeichnen sich die erzielten Ergebnisse durch eine hohe Aussagescharfe - allerdings nur in eng begrenzten Gultigkeitsbereichen - aus.

Discusses the objects and channels of attack in psychological warfare. Analyses Hitler's methods during World War II of undermining enemy morale and the ability to resist through four general media: spoken, written, pictorial and material. Concludes that in the future there must be trained specialists for psychological warfare, as well as training for psychological warfare the same as any other weapon of war.